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Journal : KOLONI

Efektivitas Penggunaan Antihipertensi Pada Pasien Diabetik Nefrotik Anisa Dwirizky Abdullah; Nurpatwa Wilda Ningsi; Riska Mayangsari; Aulia Rahmi Latif
KOLONI Vol. 2 No. 2 (2023): JUNI 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v2i2.118

Abstract

Nephropathy diabetic is a microvascular complication of diabetes, which can lead to end-stage renal disease (ESRD) in both type 1 and type 2 diabetes mellitus. Management of hypertension in ND significantly contributes reducing effect of cardiovascular morbidity and mortality, as well as inhibiting the development of kidney damage. This study was an analytical observational study with prospective and retrospective cohort design using comparative study between amlodipine, the combination of amlodipine valsartan and the combination of amlodipine telmisartan in ND at Dr. Wahidin Sudirohusodo Hospital, Makassar which aimed to obtain a comparison of treatment effectiveness. Treatment’s effectivity was measured based on the average decrease in blood pressure while the quality of life in cost utility analysis was measured by the Short Form-36 (SF-36). Sampling was done by purposive sampling technique and obtained 62 samples. The results showed that the combination amlodipine valsartan had better effectiveness than using amlodipine-valsartan and amlodipine alone in reducing systolic blood pressure and diastolic blood pressure for nephropathy diabetic. Keywords: Hypertension, Nephropathy diabetic, blood pressure
Stabilitas Sediaan Lotion Ekstrak Herba Sawi Langit (Vernonia cinerea (L.) Less) Dengan Menggunakan Stearil Alkohol Sebagai Emulgator Auliah Rahmi Latif; Anisa Dwirizky Abdullah
KOLONI Vol. 2 No. 2 (2023): JUNI 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v2i2.304

Abstract

Stability Test of Preparation Lotion extract Sawi Langit (Vernonia cinerea (L) Less) herbal with stearyl Alcohol as an emulsifier. The purpose of this study was to determine the ability of stearyl alcohol as an emulsifier in the preparation of lotion extract Sawi langit herba as well as to determine the level of stability of the preparation. The lotion is formulated with a variety of emulsifier stearyl alcohol concentrations of 1% b/b, 3% b/b, and 5% b/b. Evaluation lotion was conducted for 2 weeks include: organoleptic preparations have colors, shapes, and smells of stable, power of dispersive at concentration 1% b/b and 3% b/b qualify the power of dispersive preparation lotion is 7cm-14cm, the pH value of 50C storage stable and 250C storage stable at concentration of 1% b/b and 3% b/b because it has suitable pH of the skin 4.5-6.5 and pH of good lotion is 4.5-8.0. Keywords: Stability Test, Lotion, Extracts Sawi Langit Herbal, stearyl alcohol emulsifier