<![CDATA[Filariasis is a chronic infectious disease caused by filarial worms and transmitted by mosquitoes. Filariasis cases in Indonesia in 2019 were 10,758 cases, and in Tambrauw Regency in 2023 there were 30 cases, 14 of which were in Kwoor District. The majority of the people in Kwoor District have primary education, and have houses near the livestock pens. The study aims to determine the relationship between knowledge, attitudes, physical environment and adherence to taking medication with the incidence of filariasis in Kwoor District, Tambrauw Regency. This type of research is quantitative with a cross-sectional design, conducted in the Kwoor District, Tambrauw Regency on February 27-March 4, 2023. The population and sample are all 105 household heads, taken by total sampling. Data was collected using questionnaires and observation sheets. Data were analyzed by Chi Square test with ? = 0.05. The test results obtained were knowledge p-value = 0.752, attitude p-value = 0.030, compliance with taking medication p-value = 0.620, physical environment p-value = 0.071. The conclusion of the study is that there is a relationship between attitude and the incidence of filariasis and there is no relationship between knowledge, adherence to taking medication and the physical environment with the incidence of filariasis. It is recommended for the health center to increase counseling and community supervision, for the community to sleep using mosquito nets, pay attention to the surrounding environment, future researchers to conduct similar research with variables of health status, occupation and geographical location.]]>
