Article Per Year (5 Year)
p-Index From 2019 - 2024
0.23
P-Index
This Author published in this journals
All Journal MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan
Dimas Ikhsan Airlangga
Brawijaya University, Malang, East Java, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Effects of The Combination of Seluang Fish (Rasbora spp.) and Pasak Bumi (Eurycoma Longifolia Jack) on Systemic Inflammation and Neurotransmitter in Stunting Model Rat (Rattus Novergicus) Didik Dwi Sanyoto; Hendra Nur'amin; Triawanti Triawanti; Dimas Ikhsan Airlangga; Gastin Gabriel Jangkang
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 10, No 1 (2023): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.10.1.2023.27-39

Abstract

Background:  Stunting causes growth and development issues which are characterized by a systemic inflammatory response and neurotransmitter disorder. The South Kalimantan natural resources i.e. extracts of Pasak Bumi (Eurycoma longifolia Jack) and seluang fish have the potential as a modified therapy for stunting management.Objective: To analyze the effect of Pasak Bumi and seluang fish administration in overcoming systemic inflammation and neurotransmitter disorders in the stunting rats model.Methods: Rats were divided into six group i.e Positive Control (KP): Stunting rats + placebo + standard feed; (P1): stunting rats + 70% EPB 15 mg/kg body weight (BW) + standard feed; (P2): Stunting rats + DHA 1 mg/kg BW + standard feed; (P3): Stunting rats + EPB 15 mg/kg BW + DHA 1 mg/kg BW + standard feed; (P4): Stunting rats + seluang fish; (P5): Stunting rats + EPB 15 mg/kg BW + seluang fish for 5 weeks; Parameters measured were levels of IL-6, TNF-α, and serotonin.Results: There were significant differences in levels of TNF-α (p = 0.000) and serotonin (p = 0.000).Conclusion: The administration of Pasak Bumi extract and seluang fish was able to inhibit systemic inflammation and neurotransmitter dysregulation.
Co-Authors Didik Dwi Sanyoto Gastin Gabriel Jangkang Hendra Nur'amin Triawanti Triawanti