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PATTERN OF ANTERIOR UVEITIS IN KMN EYECARE Kevin Kevin; Rifna Lutfiamida
International Journal of Retina Vol 6 No 2 (2023): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2023.vol006.iss002.245

Abstract

Introduction: Anterior uveitis is the most common form of uveitis, but there are relatively few anterior uveitis studies in Indonesia. The purpose of this study is to analyze the pattern of anterior uveitis in KMN EyeCare. Methods: This is a retrospective analytic descriptive study. The samples are new patients diagnosed with anterior uveitis in KMN EyeCare between 2019 – 2021. Data collected from medical records are age, gender, clinical manifestation, etiology, and visual outcome. Result: Two hundred fifty-three (253) patients are included in this study. The most common manifestations of anterior uveitis are keratic precipitates (34%), posterior synechiae (23.3%), hypopyon (7.9%), increased IOP (7.1%), and secondary cataract (6.3%). Visual outcome more than 0.5 in 90.1% of patients and below 0.5 in 9.9% of patients. The etiology is non-infectious autoimmune-related (46.7%) consists of HLA-B27 related, and rheumatoid arthritis; followed by infectious etiology (36%) consisting of herpetic, tuberculosis, cytomegalovirus, and idiopathic (17.3%). HLA-B27 anterior uveitis is more likely to affect males than females with a statistically significant p<0.05. Conclusion: The most common etiology of anterior uveitis is non-infectious autoimmune-related, especially HLA-B27-related anterior uveitis. The HLA-B27-related anterior uveitis is predominantly in males. Keratic precipitates, posterior synechiae, and hypopyon are common clinical manifestations of anterior uveitis. The visual outcomes are good in this study.
NON-NECROTIZING DIFFUSE ANTERIOR SCLERITIS SEBAGAI MANIFESTASI OKULER TERISOLASI DARI LUPUS ERYTHEMATOSUS SISTEMIK: LAPORAN KASUS Kara Citra Kalandra; Rifna Lutfiamida
Majalah Oftalmologi Indonesia Vol 49 No 2 (2023): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v49i2.100763

Abstract

Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disorder with heterogeneous clinical manifestation in numerous organ systems, including the eye. Ocular involvements have been reported in up to one-third of patients with SLE, although scleritis is considered a less common manifestation of the disease found in only about 1% of cases Case Report: A 46-year-old female patient presented with a painful right eye for 1 week. She reported having the same symptom last year which resolved without treatment. There was no known history of systemic immune-mediated diseases and no prior ocular trauma. Ophthalmological examination revealed dilatation of deep scleral vessels on the right eye. The patient tested positive for the antinuclear antibody and anti-double-stranded deoxyribonucleic acid tests. She was diagnosed with non-necrotizing diffuse anterior scleritis caused by SLE and was treated with topical prednisolone acetate and systemic methylprednisolone. After 1 week of treatment, the patient showed an improvement in ocular signs and symptoms. Discussion: Scleritis is a rare inflammatory disease usually associated with systemic immune-mediated diseases such as SLE. It can cause significant visual loss and may be life-threatening. We reported a non-necrotizing diffuse anterior subtype of scleritis presented as an isolated manifestation in SLE, which benefited from early diagnosis and treatment of corticosteroids. Conclusion: Scleritis may present as an early or isolated manifestation of systemic immune-mediated disease. Therefore, a comprehensive examination is of the essence to exclude multisystem disease and treat the underlying cause even when there is no systemic manifestation.