Article Per Year (5 Year)
p-Index From 2019 - 2024
0.751
P-Index
This Author published in this journals
All Journal Journal of Pharmaceutical and Sciences. Leuser Journal of Environmental Studies Grimsa Journal of Science Engineering and Technology
Mahmudi Mahmudi
Department Of Pharmacy, STIKES Assyifa Aceh, Aceh, Indonesia 23242
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Energy Engineering Environmental Science Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Other

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Formulasi dan uji sifat fisik lulur krim ekstrak etanol bunga kecombrang (Etlingera eliator (Jack) R.M. Smith) Rina Kurniaty; Asri Ainun; Mutia Farida; Saiful Azhari; Salman Salman; Mahmudi Mahmudi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.223

Abstract

Kecombrang plant (Etlingera eliator (Jack) R.M. Smith), has bioactive compounds of polyphenols, alkaloids, flavonoids, steroids, saponins and essential oils. The purpose of this study, to make a cream scrub formulation from ethanol extract of kecombrang flowers that meets the standards and benefits on the skin. The method of this study, by varying the concentration of ethanol extract of kecombrang flowers 5% and 10% with modified formulations adding amylum oryzae as a scrub and without the addition of amyulum oryzae. The results of the 28-day study based on the parameters, in the organoleptical test had a stable shape, odor, and color, in the homogeneity test showed a homogeneous preparation, the pH test had a stable value of 7, the spreadability test had an average value of 5 cm, stable results in room or low temperature storage (2-8oC). Hedonic test results with parameters, aroma, texture, color, and effectiveness, namely formulation I 10% with an average scale value of 5, which means very like is a formulation with the addition of amylum oryzae as a scrub. Formulation results with the addition of amylum oryzae affect the preparation of abrasive formulations. The results of the skin effectiveness test, in the moisture test using a skin analyzer with an average value of moist volunteer skin at week 4, and the volunteer's skin color is slightly brighter. In conclusion, the cream scrub formulation has a good formulation, kecombrang flower extract has the effect of brightening the skin and moisturizing the skin.
Method Validation for Pesticide Residues on Rice Grain in Aceh Besar District, Indonesia Using Gas Chromatography-Electron Capture Detector (GC-ECD) Agus Winarsih; Rinaldi Idroes; Utari Zulfiani; Muhammad Yusuf; Mahmudi Mahmudi; Saiful Saiful; Sunarti Abd Rahman
Leuser Journal of Environmental Studies Vol. 1 No. 1 (2023): July 2023
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/ljes.v1i1.37

Abstract

Analysis of pesticide residues in rice in Aceh Besar District using the Gas Chromatography – Electron Capture Detector (GC-ECD) method has been carried out. This study aims to validate the analytical method and determine the pesticide residue levels of Dichlorvos, Dimethoate, Bifenthrin, and λ-Cyhalothrin in rice samples. Rice samples in branded rice were taken from the Districts of Want Jaya, Indrapuri, Darussalam, Suka Makmur, Simpang Tiga, Kuta Baro, and ground using a grinder. The powder sample was extracted by the QuEChERS method and analyzed by GC-ECD. The results of the linearity test have met the requirements with the coefficient of determination (R2), which is an average of 0.98. The LOD values ranged from 0.013 to 0.017 mg/kg, while the LOQ ranged from 0.022 to 0.079 mg/kg. The results of precision and reproducibility (% RSD, n = 6) show the values of 0.56 - 1.26% and 1.14 - 2.19%, respectively, and the accuracy value (%Recovery) shows the results of 99.71 - 101.84%, with an RSD value of 2.42 - 3.59%, meet the requirement of 20%. The results of the analysis of the sample showed that sample A had a large %Recovery value in the Dichlorvos analyte, namely 139.10%, with the calculation that the Dichlorvos analyte contained 0.0206 mg/Kg. This value has not passed the MLR set by the European Food Safety Authority, which is 0.2 mg/Kg. In the other rice samples, no pesticide residue analytes were detected. The calculation of %Recovery of each analyte in the spiked sample ranged from 80-101%, which indicated that the pesticide residue analysis carried out had good accuracy, namely the requirement of 70-120%.
Assessing Heavy Metal Contamination in Traditional Herbal Medicine (Jamu) by Atomic Absorption Spectrophotometry Mahmudi Mahmudi; Mutiara Annisa; Mutia Farida; Muhammad Yusuf; Saiful Azhari; Yunda Fachrunniza
Grimsa Journal of Science Engineering and Technology Vol. 1 No. 1 (2023): October 2023
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v1i1.4

Abstract

Heavy metal contamination of traditional herbal medicine (jamu) is a threat to humans, especially at levels above known threshold concentrations. Traditional herbal medicine found in Banda Aceh City – Indonesia, polluted by heavy metals cadmium (Cd), lead (Pb), and mercury (Hg) was performed. Heavy metal analysis used Flame - Atomic Absorption Spectrometry (FAAS) and Chemical Vapor Generation - Atomic Absorption Spectrometry (CVG - AAS) methods. The validation of the method was performed to obtain more accurate heavy metal analysis results for the samples. Heavy metal contamination, especially Pb metal, with concentrations of 4.32 ± 0.14 mg/Kg to 29.25 ± 0.24 mg/Kg. The Cd metal contamination was only found in herbal medicine sample E with a concentration of 0.80 ± 0.02 mg/Kg, above the threshold. The Hg metal contamination was also found with concentrations of 0.20 ± 0.01 to 2.14 ± 0.06 mg/Kg, and some were not detected. The government should be very concerned about stopping the distribution of herbal medicine that can be harmful to health and should inspect drug stores that still sell herbs that do not have established standards.
Vegetables, Heavy metals, FAAS, Kajian Cemaran Logam Berat Timbal (Pb), Kadmium (Cd), Dan Merkuri (Hg) Pada Sayuran Di Daerah Pertambangan Aceh Jaya Secara Spektrofotometri Serapan Atom. Rina Kurniaty; T.M. Dayan Adiyana; Muhammad Yusuf; Mahmudi Mahmudi
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 3 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i3.448

Abstract

Heavy metal contamination in vegetables poses a threat to humans, especially at predetermined thresholds. In this study, Pb, Cd, and Hg metals were analyzed using Flame - Atomic Absorption Spectrometry (F-AAS) and Vapor Generation Accesory - Atomic Absorption Spectrometry (VGA-AAS) methods at mining areas in Krueng Sabee Sub-District, Aceh Jaya District, Aceh Province. Method validation was conducted to obtain accurate heavy metal analysis results on the samples. The results showed that the highest Pb metal contamination was found in cassava leaf I sample with levels of 2.44 ± 1.33 mg/Kg and the lowest was found in spinach III sample with levels of 0.15 ± 0.07 mg/Kg. The high Pb content was also found in kale I and spinach I samples obtained in areas close to the mining area with levels of 1.07 ± 0.59 mg/Kg and 0.93 ± 0.50 mg/Kg, respectively. The highest Cd metal contamination content was found in kale II samples with levels of 0.11 ± 0.01 mg/Kg and the lowest Cd metal contamination with levels of 0.02 ± 0.01 mg/Kg was found in cassava leaf II samples. The highest Hg metal content of 0.58 ± 0.12 mg/Kg was found in cassava leaf I sample and the lowest level was 0.04 ± 0.02 mg/Kg owned by spinach III sample. Contamination of Hg metal in all vegetable samples showed levels that were above the established SNI 7387 (2009) quality standard of 0.03 mg/Kg. The quality standards for Pb and Cd metal contamination are 0.5 mg/Kg and 0.2 mg/Kg, respectively.  This study shows the need for government monitoring of heavy metal contamination in agricultural areas near mining activities to ensure safe food consumption.
Co-Authors Agus Winarsih Asri Ainun Muhammad Yusuf Muhammad Yusuf Muhammad Yusuf Mutia Farida Mutiara Annisa Rina Kurniaty Rina Kurniaty Rinaldi Idroes Saiful Azhari Saiful Saiful Salman Sunarti Abd Rahman T.M. Dayan Adiyana Utari Zulfiani Yunda Fachrunniza