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H, Arief R
Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

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The Antidepressant Effects of (Arcangelisia flava (l.) Merr) Water-Soluble Extract in Balb-C Mice Reviewed from Immobility Time by Forced A, Tiara; H, Arief R; Sudarsono, Sudarsono
Biology, Medicine, & Natural Product Chemistry Vol 3, No 2 (2014)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (390.776 KB) | DOI: 10.14421/biomedich.2014.32.65-67

Abstract

This study was conducted to examine / determine the antidepressant effects of (Arcangelisiaflava L.) on immobility time of the white male mice strain Balb-c by the forced swim test method. The method of research using laboratory animals such as 25 micewas divided into 5 groups. As a negative control group was only given distilled water ad libitum. Amitryptiline was used as the positive control group; the experiment group was a water-soluble extract of A.flava by  multiple doses. The results showed that the best antidepressant effects were312 mg/kgBW ; it had a minimum of immobility time compared with the other groups.
Co-Authors A, Tiara Sudarsono, Sudarsono