<![CDATA[Alzheimer's disease is a degenerative disease associated with memory loss, communication difficulties, mental health, thinking skills, and other psychological disorders that affect a person's daily activities. Alzheimer's disease is a disease that causes disability for people aged 70 years and over and is the seventh highest contributor to death in the world. However, until now there has not been found an effective treatment to cure Alzheimer's disease. Thus, early detection of Alzheimer's disease is very important so that sufferers of Alzheimer's disease can immediately receive intensive medical care so as to reduce the death rate from Alzheimer's disease. One method that can be used to detect Alzheimer's disease is by utilizing a machine learning algorithm model. The machine learning model in this study was carried out using the Decision Tree C4.5 algorithm classification method based on Binary Particle Swarm Optimization (BPSO). The C4.5 Decision Tree algorithm is used to classify Alzheimer's disease, while the BPSO algorithm is used to perform feature selection. By performing feature selection with the BPSO algorithm, the results show that the BPSO algorithm can improve accuracy and can increase the performance of the C4.5 algorithm in the Alzheimer's disease classification process. The results of the accuracy of the C4.5 algorithm using the BPSO feature selection are greater, namely 98.2% compared to the C4.5 algorithm without BPSO feature selection, which is only 96.4%. ]]>
