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All Journal Medical Journal of Indonesia Jurnal Plastik Rekonstruksi
Anggrahita, Tasya
Department of Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
Civil Engineering, Building, Construction & Architecture Medicine & Pharmacology Other

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Chlorhexidine-alcohol versus povidone-iodine as preoperative skin preparation to prevent surgical site infection: a meta-analysis Anggrahita, Tasya; Wardhana, Aditya; Sudjatmiko, Gentur
Medical Journal of Indonesia Vol 26, No 1 (2017): March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (451.733 KB) | DOI: 10.13181/mji.v26i1.1388

Abstract

Background: Surgical site infection remains substantial problems to surgeons and patients as it increases the morbidity, mortality, length of stay, hospital cost, rate of re-admission, and rate of re-surgery. This study aims to compare the use of chlorhexidine-alcohol versus povidone-iodine for preoperative skin preparation to prevent surgical site infection.Methods: The literature search was conducted through the PubMed database on November 2015. Included studies were RCTs with the year of publication up to 2015 which compared the use of chlorhexidine-alcohol versus povidone-iodine in its effectiveness reducing surgical site infection in adult patients. The quality of the study was assessed using Jadad Score. A meta-analysis was conducted in the included study to obtain a pooled estimate of the effect size. The evidence of heterogeneity and publication bias was also assessed.Results: Six RCTs with a total of 2,080 patients were included in the meta-analysis. It showed that the use of chlorhexidine-alcohol was associated significantly with fewer SSIs (pooled risk ratio=0.60 (95% CI=0.45-0.79)) and fewer positive skin culture results (pooled risk ratio, RR=0.38 (95% CI=0.28-0.51)) compared with povidone iodine.Conclusion: Preoperative skin antisepsis with chlorhexidine is more effective than povidone-iodine in preventing surgical site infection.
Pregnancy Unawareness and Risk Factors in Cleft Sari, Vania Aramita; Anggrahita, Tasya
Jurnal Plastik Rekonstruksi Vol. 2 No. 2 (2013): April Issue
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (377.064 KB) | DOI: 10.14228/jpr.v2i2.151

Abstract

Background : The etiology of the cleft lip and palate (CLP) are still debated among researchers. Early pregnancy awareness is essential since the facial formation occurs in the first eight-week of gestation period. This study aims to compare pregnancy awareness and risk factors associated with CLP. Method : A descriptive cross-sectional study on 103 mothers whose child suffered from non-syndromic CLP (cases) was compared to 157 mothers whose child is normal (control). Parameters evaluated were pregnancy awareness during early pregnancy and CLP risk factors, including oral contraceptive (OC), absence of vitamin supplementation, smoking, and alcohol use within the first eight-week of gestation period. Family history and maternal age were also assesed. Result : The rates of late pregnancy awareness were 10-folds higher in cases, with the scale of 65% compared to 6.5% (p value <0.0001). The use of OC in cases group were 22.6-folds higher (13.6% versus 0.6%), the absence of vitamin supplementation were found to be 123-folds higher as well (73.8% compared to 0.6%). An inverted data were found in the smoke exposure parameter, which was higher in control (27.7% versus 10.7%). In confounded factors, advanced maternal age in the cases soared (37.9% compared to 25.3%), positive family history of cleft were discovered in 24.3% of mother with cleft children. Conclusion : Most cases were categorized in late pregnancy awareness. Higher rates of positive family history and advanced maternal age in cases group were also found.
Co-Authors Sari, Vania Aramita Sudjatmiko, Gentur Yundari, Yundari