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WASPADA PENYAKIT LIVER DAN KANKER HATI MAKA PERLU PEMBERIAN VAKSIN HEPATITIS B Abdul Karim; Kahermasari; Cucu Mutia; Anellia Putri T
Scientica: Jurnal Ilmiah Sains dan Teknologi Vol. 2 No. 4 (2024): Scientica: Jurnal Ilmiah Sains dan Teknologi
Publisher : Komunitas Menulis dan Meneliti (Kolibi)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.572349/scientica.v2i4.1189

Abstract

Hepatitis virus akut adalah infeksi sistemik yang dominan menyerang hati. Hampir semua kasus hepatitis virus akut disebabkan oleh salah satu dari lima jenis virus yaitu: virus hepatitis A (HAV), virus h epatitis B (HBV), virus hepatitis C (HCV), virus hepatitis D (HDV) dan virus hepatitis E (HEV). Gambaran klinis hepatitis virus sangat bervariasi mulai dari asimtomatik sampai yang sangat berat yaitu hepatitis fulminan yang dapat menimbulkan kematian. Selain itu, gejala juga bisa bervariasi dari infeksi persisten subklinis sampai penyakit hati kronik progresif cepat dengan sirosis hepatis dan karsinoma hepatoseluler yang umum ditemukan pada tipe virus yang ditransmisi melalui darah (HBV, HCV, dan HDV). Hepatitis virus akut merupakan urutan pertama dari berbagai penyakit hati di seluruh dunia. Penyakit tersebut ataupun gejala sisanya bertanggung jawab atas 1- 2 juta kematian setiap tahunnya. Banyak episode hepatitis dengan klinik anikterik, tidak nyata atau subklinis. Secara global virus hepatitis merupakan penyebab utama viremia yang persisten. Di Indonesia berdasarkan data yang berasal dari rumah sakit, hepatitis A masih merupakan bagian terbesar dari kasus-kasus hepatitis akut yang dirawat yaitu berkisar dari 39,8-68,3%. Peningkatan prevalensi anti HAV yang berhubungan dengan umur mulai terjadi dan lebih nyata di daerah dengan kondisi kesehatan di bawah standar. Lebih dari 75% anak dari berbagai benua Asia, Afrika, India, menunjukkan sudah memiliki antibody anti-HAV pada usia 5 tahun. Sebagian besar infeksi HAV didapat pada awal kehidupan, kebanyakan asimtomatik atau sekurangnya aniktertik
The Development and Application of Biosensors in Medical Diagnostics in Indonesia Sabrina Hayati; Abdul Karim
International Journal of Public Health Vol. 1 No. 3 (2024): September : International Journal of Public Health
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijph.v1i3.68

Abstract

Biosensors are analytical devices that combine biological sensing elements with physicochemical detectors to provide rapid, accurate, and cost-effective solutions for medical diagnostics. Globally, these devices have revolutionized the detection and monitoring of diseases, significantly impacting patient outcomes. In Indonesia, the adoption and development of biosensor technology have accelerated over the past decade, particularly in response to the growing healthcare needs and the government's push for technological innovation. This study aims to review and analyze the development and application of biosensors in Indonesia medical diagnostics sector between 2014 and 2024. The research focuses on identifying key technological advancements, the integration of biosensors into healthcare, the challenges faced in their development and deployment, and the prospects for future growth. The study employs a comprehensive literature review and analysis of scientific publications, industry reports, and government documents related to biosensor technology in Indonesia. The review covers the evolution of biosensing materials, point-of-care testing applications, integration with digital health technologies, and regulatory frameworks. Data were synthesized to provide a detailed overview of the current state of biosensor technology and its impact on medical diagnostics in Indonesia. The findings indicate significant advancements in biosensor technology, particularly in the development of novel nanomaterials, the integration of biosensors with mobile health (mHealth) platforms, and the expansion of point-of-care testing (POCT) for infectious diseases. However, the sector faces challenges, including technological limitations, regulatory hurdles, and economic constraints, which have slowed the widespread adoption of biosensors in clinical settings. Despite these challenges, the future of biosensors in Indonesia appears promising, with continued investment and innovation expected to drive further advancements in this field.