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Formulasi Sediaan Sunscreen dari Ekstrak Etanol Daun Ubi Jalar Ungu (Ipomoea batatas L.) Rosiana Rizal; Salman; Kiki Ariyani
Jurnal Sains Farmasi Dan Kesehatan Vol. 1 No. 1 (2023): Mei - Agustus
Publisher : CV. ITTC INDONESIA

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Abstract

Ultraviolet rays that have the most influence on skin health are ultraviolet B radiation because they have the strongest effect in causing photodamage to the skin. One way to minimize skin damage from ultraviolet exposure is the need for antioxidant compounds. Ipomoea batatas leaves have potential as antioxidant agents because their phytochemical components are higher than the tuber, contain secondary metabolites of flavonoids, phenolics, saponins and alkaloids. This study aims to determine the ethanolic extract of Ipomoea batatas leaf can be formulated in a cream dosage form that meets the requirements and to determine the difference in the concentration of ethanolic extract of Ipomoea batatas leaf can affect the value of the sun protection factor as a sunscreen. Extracted by maceration of 70% ethanol which was formulated in the form of sunscreen with an extract concentration of 2% (F1), 4% (F2) and 6% (F3) and followed by an in-line SPF test using UV-Vis spectrophotometry. The results of this study indicate that the preparation meets the requirements of organoleptic, homogeneity, pH, dispersibility, adhesion and viscosity during a storage period of 28 days and the measurement results of the preparation with a concentration of 500 ppm at a wavelength of 290-320 nm for each formula. SPF values were obtained at F1 4.4 (moderate protection), F2 5.5 (medium protection) and F3 7.6 (extra protection). This research can be said that the ethanolic extract of purple sweet potato leaves can be formulated in the form of cream preparations and cream preparations at F1, F2 and F3 meet the requirements of a good cream.
Formulasi Sediaan Spray Gel Ekstrak Etanol Pegagan (Centella asiatica (L.) Urban ) Dan Uji Daya Tabir Surya Rosiana Rizal; Salman; Vadilah Maharani
Jurnal Sains Farmasi Dan Kesehatan Vol. 1 No. 1 (2023): Mei - Agustus
Publisher : CV. ITTC INDONESIA

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Abstract

Skin damage is caused by sunlight which interferes with the health of human skin, so it needs sunscreen protection, where sunscreen has the ability to protect the skin. Pegagan is a plant that contains many secondary metabolites, one of which is flavonoids which can be used as sunscreen. The research was conducted to formulate a spray gel preparation of pegagan (Centella asiatica (L.) Urban) ethanol extract which has an SPF value for UV radiation protection. Pegagan was extracted by maceration method using 70% ethanol as solvent. The extracts obtained were made into spray gel preparations with concentrations of pegagan ethanol extract F1(2%), F2(4%), and F3(6%). Spray gel from pegagan ethanol extract was evaluated for 28 days including organoleptic, homogeneity, viscosity, pH, adhesive dispersion, and spraying pattern. Determination of the results of sunscreen power using uv-vis spectrophotometry method. The results showed that all of the spray gel preparations had met the requirements. The preparation of pegagan ethanol extract spray gel has a slightly thick texture, dark green color, has a characteristic aroma of pegagan and is homogeneous. It has a viscosity value of 1650,75 cPs-1804,5 cPs, with a pH value of 5,7. The results of the evaluation of the spreadability of sticking to the skin while the spraying pattern is elongated and spread. The activity of sunscreen spray gel ethanol extract of pegagan was measured at a wavelength of 290-320 nm with an interval of 5, the best SPF value was found in formula 3 (6%) with an SPF value of 18,32 including the ultra category.