Septi Wulandari
Program Studi S1 Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Bengkulu

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Formulasi Dan Optimasi Sediaan Gel Ekstrak Etanol Kol Ungu (Brassica oleracea L. Var. Capitata F. Rubra) dengan Basis Carbomer nofran putra pratama; Endah Kurniawati; Tira Risa Oktapiya; Zerli Rahmawati; Septi Wulandari
BENCOOLEN JOURNAL OF PHARMACY Vol. 4 No. 1 (2024): April
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v4i1.33999

Abstract

Purple cabbage (Brassica oleracea L. Var. Capitata F. Rubra) is known to have anti-inflammatory activity, so it can be used as a medicine to treat inflammation, especially in breastfeeding mothers. To make it easier to use, it is made into a gel formulation. One of the compounds in purple cabbage is anthocyanin which is in the form of glycosides bound to sugar molecules (cyanidin-3 diglucoside-5-glucoside). These compounds have important effects on the body, one of which is anti-inflammatory. To make it easier to use, it is made into a gel formulation. One of the bases used in the formulation of gels is carbomer. Carbomer has better characteristic in terms of the release of active substances compared to other gel bases. The purpose of this study was to make a gel formulation and to determine the effect of purple cabbage extract gel characteristic on the stability of the physical properties of the preparation. The gel was made using a carbomer base with various extract concentrations of 2.5%, 5% and 7.5%. The gel was tested for its physical characteristic including organoleptic, viscosity, pH, dispersionfor 21 days as well as a preference test. The analytical method used is ANOVA with a 95% confidence level and a Likert scale as a comparative test for the formulation based on the respondents' preferences. The results of the gel formulation using a carbomer base with variations in the concentration of the extract showed that the physical characteristic test of all variables showed that all the formulas met the requirements of the physical preparation, namely homogeneous, viscosity with a value below 50,000 cps, a suitable pH of less than 6, and dispersion in line with the viscosity value. The results of the preference test showed that F2 had the best acceptance and many respondents chose it. The conclusion of this study is that all formulas show results that are in accordance with the requirements of the gel preparation. The difference in extract concentration did not show a significant difference to the length of storage time
PELATIHAN PENGENALAN DAN PENGELOLAAN OBAT DALAM RUMAH TANGGA DI YAYASAN SENAM JANTUNG SEHAT PROVINSI BENGKULU Reza Pertiwi; Septi Wulandari; Reni Susanti; Farah Az Zahra; Iyas Nur Khaliq; Afiska Mutyarini; Imelda Sihombing
Jurnal Pengabdian Kepada Masyarakat Bersinergi Inovatif Vol. 2 No. 1 (2024): Jurnal Pengabdian Kepada Masyarakat Bersinergi Inovatif
Publisher : PT. Gelora Cipta Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61674/jpkmbi.v2i1.186

Abstract

Pengelolaan obat di rumah tangga pada masyarakat masih banyak yang tidak tepat dalam upaya swamedikasi. Hal tersebut beresiko memberikan dampak buruk kesehatan diri maupun lingkungan. Penting bagi masyarakat memiliki pengetahuan yang benar terkait obat agar terhindar dari dampak buruk tersebut. Oleh sebab itu, tim pengabdian melakukan kegiatan pengabdian yang terdiri dari penyuluhan tentang pengenaln obat dan pengelolaan obat di rumah tangga. Pengabdian ini bertujuan untuk meningkatkan wawasan dan keterampilan masyarakat mengenai penggunaan dan pengelolaan obat yang benar. Salah satu cara pengelolaan obat yang baik dan benar adalah dengan menerapkan program DAGUSIBU (DApatkan, GUnakan, SImpan, BUang) dalam pengelolaan obat rumah tangga. Pengabdian dilaksanakan pada masyarakat terkhususnya ibu-ibu peserta Senam Jantung Sehat di Stasion Kota Bengkulu. Evaluasi pengabdian dilakukan melalui sesi tanya jawab sebelum dan sesudah edukasi terkait pengenalan dan pengelolaan obat di rumah tangga. Hasil evaluasi observasi memperlihatkan semua peserta sudah mampu mempraktekkan dan menjelaskan cara pengelolaan obat di rumah tangga pada aspek menggunakan, menyimpan dan membuang obat. Dengan memahami dan menerapkan cara pengelolaan obat yang benar di rumah tangga maka tujuan pengobatan dapat tercapai serta tidak menimbulkan kerusakan lingkungan.