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All Journal ad-Dawaa : Journal of Pharmaceutical Sciences
Pratiwi, Afrianty
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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Effects of Enhancment Span-60 of Vernonia amygdalina Leaves Extract-loaded Niosomes Pratiwi, Afrianty; Syahrana, Nur Azizah; Ismail, Isriany; Arsul, Muhammad Ikhlas
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 6 No. 2 (2023)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v6i2.45956

Abstract

Introdiction: Niosomes are a promising drug carrier because of their bilayer structure and the fact that they are produced by the self-association of nonionic surfactants and cholesterol in an aqueous phase. Niosomes are non-toxic, biodegradable, and compatible with human cells. Aims: This research aimed to create niosomes from V. amygdalina leaves and investigate how span 60 addition affects niosome properties. Methods: Extraction V. amygdalina using maceration, niosomes synthesized using a thin-film hydration process, and characterization performed by SEM, particle size, polydispersity index, zeta potential, and FTIR. Conclusion: V. amygdalina succesfully to loaded into niosomes. Span-60 with various concentration affected of characterization of niosomes. Increased span-60 increasing particle size, polydispersity index, and %EE.
Co-Authors Arsul, Muhammad Ikhlas Isriany Ismail Syahrana, Nur Azizah