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All Journal Health Information : Jurnal Penelitian Jurnal Ners
Kentanto, Given
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Potensi Penggunaan Agen Anti-Fungal Naftifine Sebagai Terapi Inovatif Tinea: Sebuah Tinjauan Literatur Titanic, Pussof Yayazucah; Arliska, Vira Geraldine; Johansen, Johansen; Kentanto, Given; Priyanto, Teguh
Health Information : Jurnal Penelitian Content Digitized
Publisher : Poltekkes Kemenkes Kendari

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Abstract

A disease with the first name "Tinea" is aninfection caused by the presence of dermatophyte fungi that can occur invarious locations of the body. Tinea corporis is a superficial fungalskin infection of the body caused by dermatophytes, specifically on thetrunk, neck, arms and legs. Other forms of tinea infection based on itslocation are on the scalp (tinea capitis), face (tinea faciei), hands(tinea manuum), groin (tinea cruris), and feet (tinea pedis). Ingeneral, there are 3 genera that can cause this condition ofdermatophytosis (tinea), namely the genera Trichophyton, Epidermophyton,and Microsporum. Currently, there are various topical anti-fungal agentsfor treating dermatophytosis (tinea). The two main classes thatrepresent the majority of available topical antifungal agents are azolesand allylamines. Overall, the allylamines (naftifine) are superior tothe azoles in activity against dermatophytes, although both areclinically effective. Therefore, in this literature review, we conductedan analysis of the effects of using naftifine in treating various typesof tinea. Study searches were conducted on various databases such asPubmed, ScienceDirect, Directory of Open Access Journals, and theCochrane Library. From the search results obtained a total of 212studies. The studies that met the inclusion and exclusion criteria werethe 3 studies analyzed in this literature review. Administration ofNaftifine showed a higher mycological cure rate, therapeuticeffectiveness, clinical symptoms, and cure rate than the control group.No adverse events were reported with any type of naftifine in allinclusion studies. Administration of naftifine is a therapy with sideeffects in treating various types of tinea(dermatophytosis).
Co-Authors Arliska, Vira Geraldine Johansen Johansen Priyanto, Teguh Sunaryo Sunaryo Titanic, Pussof Yayazucah