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Antioxidant and Antiatherogenic Responses of Black Solo Garlic in Alloxan-Induced White Rats saryono, Saryono; Proverawati, Atikah; Jehloh, Latifah
Molekul Vol 18 No 3 (2023)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2023.18.3.9027

Abstract

The association between the consumption of black solo garlic (SG) and the increase in antioxidant enzymes and the ability to prevent atherogenicity has not been studied much. This study aims to examine the antioxidant and antiatherogenic capacities of black solo garlic in aloksan induced rats. This study used a true experimental design with a pre- and post-test approach with a control group design. The sample of 30 Wistar rats was randomly divided into 6 groups: a healthy control, a negative control, treatment at doses of 6.5, 13.5, and 26 g/KgBW, and positive controls receiving vitamin C at a dose of 1 g/kgBW. The outcomes demonstrated that following the induction, MDA, CRP, LDL, and IL-6 levels increased, while SOD and GSH-Px enzyme levels decreased. After treatment with black solo garlic for 14 days, there was an increase in the enzymes SOD and GSH-Px, as well as a significant decrease in levels of MDA, IL-6, CRP, and LDL in experimental animals. The SG dose of 13.5 g/kg BW is the most effective dose in this study. The active compounds in SG function as antioxidants in preventing atherogenic events.
A Continuing Care Program at Home on Caregiver’s Role for Children with Congenital Heart Disease: A Pilot Study Wangsawat, Tidarat; Chemama, Nisreen; Hayee, Fusiyah; Jehloh, Latifah; Jaisomkom, Anyapaksorn; Tongnuang, Patcharawadee; Hayeese, Wanisa; Kuiburd, Thussaneeya; Pratiwi, Hikmi Muharromah
Jurnal Keperawatan Soedirman Vol 19 No 2 (2024): Jurnal Keperawatan Soedirman (JKS)
Publisher : Fakultas Ilmu-ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jks.2024.19.2.10903

Abstract

Caregivers should have adequate caring roles knowledge of children to increase the quality of life of children with congenital heart disease (CHD). Aim: To develop and evaluate the effect of a home-based continuing care program on the role of caregivers for children with CHD. This pilot study was a quasi-experiment with one group pre-posttest without control group design and conducted between October 2018 and September 2019 in Narathiwat, Pattani, and Yala. Thirty caregivers were recruited using a multistage random sampling technique. The program covered teaching, demonstration, and feedback equipped with a manual of CHD for six weeks. The self-developed caregiver role questionnaire was provided to evaluate caregiver care roles. The paired t-test was applied to evaluate the different scores of the caring roles before and after the program with the significant p value < 0.05. The scores of the caregivers’ roles for children with CHD after receiving the program were significantly higher than the scores before receiving the program (t = 6.20, p < .001). Continuing care programs enhance caring roles related knowledge of children with CHD. This program is recommended to apply continuously for caregivers of children with CHD at the outpatient or as part of discharge planning