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All Journal Journal of Experimental and Clinical Pharmacy (JECP) Sahabat Sosial: Jurnal Pengabdian Masyarakat International Journal of Health Sciences
Mustarin, Rahmah
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Identifikasi dan Penetapan Kadar Flavonoid Ekstrak Etil Asetat Daun Mimba (Azadiractha indica A. Juss) Metode Spektrofotometri UV- Vis Utami, Yuri Pratiwi; Imrawati, Imrawati; Mustarin, Rahmah; Mus, Suwahyuni; Jariah, Ainun
Journal of Experimental and Clinical Pharmacy (JECP) Vol 4, No 2 (2024): August 2024
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v4i2.1049

Abstract

Flavonoid terdiri dari 15 molekul yang tersusun dalam susunan C6-C3-C6 yang merupakan senyawa polifenol. Senyawa ini berbentuk kerangka karbon dan terurai menjadi dua set: C6 dan C3. Daun mimba (Azadiractha indica A. Juss) mengandung flavonoid yang memiliki sifat antioksidan, antibakteri, dan antikanker. Penelitian ini bertujuan untuk mengidentifikasi kelompok senyawa dalam daun mimba (Azadirachta indica A. Juss) dan menentukan kadar flavonoidnya. Ekstraksi dilakukan menggunakan teknik maserasi dengan pelarut etil asetat untuk mendapatkan ekstrak yang kemudian diuji melalui skrining fitokimia. Pengukuran kadar flavonoid dilakukan dengan metode spektrofotometri UV-Vis. Dari hasil ekstraksi, diperoleh rendemen ekstrak sebesar 5,83%. Hasil skrining fitokimia menunjukkan adanya kandungan flavonoid dan alkaloid. Kadar flavonoid ditentukan menggunakan kuersetin sebagai standar pembanding, dengan persamaan garis y = 0,0739x + 0,0776. Kesimpulannya, ekstrak etil asetat mengandung flavonoid dengan kadar 1,183 ± 0,018%.Flavonoids consist of 15 molecules arranged in a C6-C3-C6 configuration, which are polyphenolic compounds. These compounds form a carbon framework and are divided into two sets: C6 and C3. Neem leaves (Azadirachta indica A. Juss) contain flavonoids that have antioxidant, antibacterial, and anticancer properties. This study aims to identify the group of compounds in neem leaves (Azadirachta indica A. Juss) and determine their flavonoid content. Extraction was carried out using the maceration technique with ethyl acetate as a solvent to obtain an extract that was then tested through phytochemical screening. Flavonoid content was measured using the UV-Vis spectrophotometric method. The extraction process yielded an extract with a percentage of 5.83%. Phytochemical screening results indicated the presence of flavonoids and alkaloids. The flavonoid content was determined using quercetin as a reference standard, with the equation y = 0.0739x + 0.0776. In conclusion, the ethyl acetate extract contains flavonoids with a concentration of 1.183 ± 0.018%.
Pendampingan dan Sosialisasi dalam Pemberian Edukasi dengan Leaflet (brosur) Penggunaan Obat Tetes Telinga Suminar, Saka; Utami, Yuri Pratiwi; Surya, Sara; Mustarin, Rahmah
Sahabat Sosial: Jurnal Pengabdian Masyarakat Vol. 2 No. 4 (2024): Sahabat Sosial: Jurnal Pengabdian Masyarakat (September)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/sosisabdimas.v2i4.450

Abstract

Various drug-related problems can be caused by the community's lack of understanding about the use and proper handling of drugs. Providing education on how to use special drugs such as ear drops is very important because there are critical points in ear drops, especially in the method of instillation. Providing incomplete and unclear information on how to use drugs will result in less than optimal therapy so that the drug will not achieve the desired therapeutic effect. This community service activity aims to increase public knowledge about how to use ear drops properly. This service is carried out by providing information through leaflets and explaining directly to the community. Providing education on how to administer ear drops to the community received a good response because most people do not know how to use them properly. The presence of 36 participants and the participants who attended were very enthusiastic in listening to the explanation and actively asked questions related to the use of ear drops and their handling. This can support the realization of government programs in improving health services for the community. This counseling received significant results. Therefore, the PkM TEAM hopes that with this counseling, it can share information about the correct use and handling of ear drops with their family members.
Study of Narcotics Management in One of the Private Pharmacies in Makassar City Mustarin, Rahmah; Utami, Yuri Pratiwi; Massolo, Selpi
International Journal of Health Sciences Vol. 2 No. 2 (2024): International Journal of Health Sciences
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/ijhs.v2i2.364

Abstract

Drug management is an important aspect of management, because its inefficiency will have a negative impact on health facilities both medically and economically. Drug management includes the stages of planning, procurement, receipt, storage, delivery, destruction, control, recording and reporting. The purpose of this research is to determine the suitability of the management of Narcotic drugs in one of the Makassar City Pharmacies with the regulations stipulated in the Minister of Health Regulation No.73 of 2016 concerning pharmaceutical service standards in Pharmacies and the Food and Drug Supervisory Agency No.4 of 2018 concerning management supervision drugs, medicinal substances, narcotics, psychotropics and pharmaceutical precursors in pharmaceutical service facilities. The type of research used was descriptive using interview and direct observation methods at one of the Makassar City pharmacies. From the results of interviews and observations, the management of narcotic drugs in pharmacies is in accordance with the regulations stipulated in the Minister of Health Regulation No. 73 of 2016 concerning standards of pharmaceutical services in pharmacies and the Food and Drug Supervisory Agency No. 4 of 2018 concerning supervision of the management of drugs and materials. drugs, narcotics, psychotropics and pharmaceutical precursors in pharmaceutical service facilities.
Co-Authors Ainun Jariah Mar’atun Jannah, Imrawati, Muzakkir Baitz, Massolo, Selpi Mus, Suwahyuni Suminar, Saka Surya, Sara Utami, Yuri Pratiwi