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Peningkatan Kemampuan Motorik Halus Anak Melalui Tehnik Mozaik Menggunakan Serutan Pensil Warna Kristianti, Silvia; Asnawati, Asnawati; Haryono, Mimpira
Early Childhood Research and Practice Vol 4 No 2 (2024): Early Child Research and Practice, Januari
Publisher : Fakultas Keguruan dan Ilmu Pendidikan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/ecrp.v4i2.4708

Abstract

Penelitian Tindakan Kelas (PTK) ini bertujuan untuk mengetahui peningkatan motorik halus melalui tehnik mozaik menggunakan serutan pensil di TK Al-Karomah Lebong. Penelitian ini sebanyak II siklus dalam 4 kali pertemuan dan bimbingan pada anak-anak di TK Al-Karomah. Subjek penelitian ini adalah anak kelompok B TK Al-Karomah berjumlah 15 anak terdiri dari 9 anak perempuan dan 6 anak laki-laki. Tehnik analisis data yang di gunakan dalam penelitian ini adalah kualitatif yang di analisis di peroleh melalui observasi. Berdasarkan hasil penelitian beberapa siklus menunjukan bahwa perkembangan motorik halus anak terbukti dari indikator keberhasilan yang di capai pada siklus I mendapat nilai persentase 52% dengan kriteria Berkembang Sesuai Harapan (BSH) dan pada siklus II indikator keberhasilan menjadi 98% dengan kriteria Berkembang Sangat Baik (BSB) dengan ini artinya peningkatan motorik halus melalui tehnik mozaik menggunakan serutan pensil di TK Al-Karomah Lebong.
Evaluation of Antifungal Resistance in Candida albicans Associated to Vaginal Candidiasis Kristianti, Silvia
Sriwijaya Journal of Obstetrics and Gynecology Vol. 1 No. 2 (2023): Sriwijaya Journal of Obstetrics and Gynecology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjog.v1i2.86

Abstract

Introduction: Candida albicans is one of the opportunistic pathogenic fungi that cause candidiasis in women between the ages of 20 and 35. This infection is commonly observed, particularly in pregnant individuals and those with weakened immune systems. Candida have the ability to create a biofilm on mucous membranes, which reduces the effectiveness of antifungal medications. The objective of this study is to evaluate the efficacy of antifungal medications in inhibiting the production of biofilms by C. albicans. Methods: Candida albicans was obtained from 40 female patients diagnosed with candidiasis, specifically married women between the ages of 20 and 40, at Jayapura General Hospital in Indonesia. The antifungal medicines utilized in this investigation include amphotericin at a concentration of 10% and fluconazole at a dosage of 50 mg. Antifungal susceptibility was assessed using the microdilution technique on Mueller-Hinton agar. The crystal violet assay (CV) was used in microtiter plates to measure how much biofilm was formed. Results: Indicative inhibitory halo diameters of 1 cm and 1.5 cm from the antifungal susceptibility test show that C. albicans demonstrated reduced sensitivity to fluconazole and amphotericin B at low concentrations. At high concentrations, the inhibitory halo diameter was between 0.08 cm and 2.3 cm. Conclusion: C. albicans demonstrated reduced sensitivity to fluconazole and amphotericin B at low concentrations and had moderate biofilm formation and antifungal susceptibility against all tested products at lower and stronger concentrations.