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All Journal Grimsa Journal of Science Engineering and Technology
Patwekar, Mohsina
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Engineering Medicine & Pharmacology Physics

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GC-MS Analysis Reveals Unique Chemical Composition of Blumea balsamifera (L.) DC in Ie-Jue Geothermal Area Maulydia, Nur Balqis; Khairan, Khairan; Tallei, Trina Ekawati; Estevam, Ethiene Castellucci; Patwekar, Mohsina; Mohd Fauzi, Fazlin; Idroes, Rinaldi
Grimsa Journal of Science Engineering and Technology Vol. 1 No. 1 (2023): October 2023
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v1i1.6

Abstract

Blumea balsamifera (L.) DC. or Sembung is a flowering plant belonging to the genus Blumea of the family Asteraceae. Many pharmacological activities of this plant show potential in human therapy. In this study, an investigation was conducted on the ethanolic extract of B. balsamifera collected from a geothermal area known as Ie-Jue, in Aceh Province, Indonesia. The results showed that the ethanolic extract of B. balsamifera contained secondary metabolites of flavonoids and tannins. Chemical constituents of ethanolic extracts B. balsamifera further analysis using gas chromatography-mass spectrometry (GC-MS) show that active compounds from this plant was Proximadiol (C15H28O2) with relative area 41.76%. This research underscores the compelling potential of the Ie-Jue geothermal area as a promising reservoir of flora owing to the plant's adaptability to geothermal extremities.
Geothermal Flora and AgNPs Synergy: A Study on the Efficacy of Lantana camara and Acrostichum aureum-Infused Hand Sanitizers Harera, Cheariva Firsa; Maysarah, Hilda; Kemala, Pati; Idroes, Ghazi Mauer; Maulydia, Nur Balqis; Patwekar, Mohsina; Idroes, Rinaldi
Grimsa Journal of Science Engineering and Technology Vol. 2 No. 2 (2024): October 2024 (In Press)
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v2i2.38

Abstract

Hand hygiene is an important factor that needs to be observed in controlling the spread of diseases transmitted through hand-to-hand contact. Synthesis of silver nanoparticles from tembelekan (Lantana camara) and paku laut (Acrostichum aureum) using the green synthesis method has good antibacterial activity against Staphylococcus aureus and Escherichia coli bacteria. Therefore, a preparation formulation was made, namely hand sanitizer, which is still rarely used. Formulations that have successfully entered the evaluation stage include organoleptic tests, homogeneity tests, spreadability tests, adhesion tests, viscosity tests, pH tests, accelerated stability tests, and irritation tests. Antibacterial activity was evaluated against bacteria Staphylococcus aureus and Escherichia coli. The hand sanitizer is formulated to contain 5% tembelekan AgNPs (F1); paku laut AgNPs 5% (F2); and a combination of 2.5% paku laut AgNPs and 2.5% tembelekan AgNPs. The resulting hand sanitizer has good organoleptic characteristics, except for the color of the preparation, which changed during the accelerated stability test. Test results for pH, adhesion, spreadability, viscosity, and homogeneity of hand sanitizer meet the requirements of a good test. Irritation tests on ten volunteers showed no irritation reaction. Antibacterial tests show that hand sanitizer has bacterial antibacterial activity with an average ± standard deviation of the inhibition zone Staphylococcus aureus is 6.605±0.459(F1); 6.665±0.615(F2); 6.380±0.282(F3) dan Escherichia coli namely 6.575 ± 0.219 (F1); 6.860 ± 0.155 (F2); 6.810 ± 0.056 (F3). Making hand sanitizer AgNPs-based ingredients from plants can be used as hand sanitizer, but stabilizers are required to prevent color changes during storage.
Co-Authors Estevam, Ethiene Castellucci Harera, Cheariva Firsa Idroes, Ghazi Mauer Kemala, Pati Khairan Khairan Maulydia, Nur Balqis Maysarah, Hilda Mohd Fauzi, Fazlin Rinaldi Idroes TRINA EKAWATI TALLEI