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N UJI AKTIVITAS ANTIBAKTERI KRIM KITOSAN CANGKANG RAJUNGAN (Portunus pelagicus) TERHADAP BAKTERI Propionibacterium acnes NURPATMAWATI, NURPATMAWATI; SUNENGSIH, SUNENGSIH
Praeparandi : Jurnal Farmasi dan Sains Vol 3 No 1 (2019): Praeparandi : Jurnal Farmasi dan Sains
Publisher : Praeparandi : Jurnal Farmasi dan Sains

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Abstract

ABSTRAK Limbah cangkang rajungan (Portunus pelagicus) diisolasi kandungan kitosannya melelui proses deproteinasi, demineralisasi dan deasetilasi. Salah satu penggunaan dari kitosan adalah sebagai antibakteri, karena memiliki polikation bermuatan positif yang mampu menghambat pertumbuhan bakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri krim kitosan cangkang rajungan (Portunus pelagicus) konsentrasi 5%, 7%, dan 9% terhadap bakteri Propionibacterium acnes. Metode penelitian yang digunakan adalah metode eksperimen pengujian aktivitas antibakteri menggunakan metode difusi sumuran diameter pervorator 0,6 cm dan media yang digunakan adalah media nutrient agar. Metode pengujian stabilitas sediaan krim kitosan cangkang rajungan (Portunus pelagicus) menggunakan metode cyling test meliputi uji organoleptik, uji homogenitas, uji pH, uji daya lekat, uji daya sebar, dan uji iritasi. Pengolahan dan analisis data dilakukan dengan uji normalitas, uji homogenitas, uji kruskal wallis dan uji mann whitney. Hasil penelitian menunjukkan bahwa krim kitosan cangkang rajungan (Portunus pelagicus) memiliki aktivitas antibakteri terhadap bakteri Propionibacterium acnes. Pada konsentrasi 9% krim kitosan cangkang rajungan (Portunus pelagicus) memiliki daya aktivitas paling besar sebagai antibakteri terhadap bakteri Propionibacterium acnes dengan diameter zona bening 1,205 cm. Krim kitosan cangkang rajungan (Portunus pelagicus) memenuhi syarat evaluasi sediaan dan dan uji stabilitas. ABSTRACT Blue swimming crab shell (Portunus pelagicus) weste can be isotated through deproteinization, demineralization and deacethylation process. One application of chitosan as an antibacterial, because it has a polycations witch can inhibit bacterial growth. This study aims to determaine the antibacterial activity chitosan cream from blue swimming crab shell (Portunus pelagicus) with concentration of 5%, 7%, and 9% against Propionibacterium acnes. The study methode used an experimental method that is by disc diffusion method with perforator diameter of 6 cm and the media used are nutrient agar media. The preparations stability testing methode of chitosan cream from blue swimming crab shell (Portunus pelagicus) using the cycling test methode including organoleptic test, homogeneity test, pH test, stickiness test, spreadability test, and irritation test. Processing and analysis of data using the normality test, homogeneity test, kruscal wallis test, and mann whitney test. The result from this study showed that the chitosan cream from blue swimming crab shell (Portunus pelagicus) has antibacterial activity against Propionibacterium acne. At a concentration of 9% the chitosan cream from blue swimming crab shell (Portunus pelagicus) has a highest antibacterial activity with diameter inhibition zone of 1,205 cm. The chitosan cream from blue swimming crab shell (Portunus pelagicus) meets the preparation evaluation requirements and stability test.
KUALITAS PELAYANAN KUNJUNGAN NEONATAL DENGAN TINGKAT KEPUASAN PASIEN DI PUSKESMAS DOLOK MERAWAN KABUPATEN SERDANG BEDAGAI Sunengsih, Sunengsih; Aritonang, Barita; Ginting, Desideria Yosepha
JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan P-ISSN : 1979-3340 e-ISSN : 2685-7987 Vol 15 No 4 (2023): DESEMBER
Publisher : NHM PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36089/job.v15i4.1643

Abstract

One of the efforts to reduce the risk of infant mortality (IMR) such as premature birth, sepsis and pneumonia, shortness of breath and trauma and LBW is the visit of newborns (neonatal). Newborn visits are one of the intervention options to reduce newborn mortality and comprehensively measure the capacity of care to provide healthy newborn delivery services for mothers and children. The reduction in infant mortality must be accompanied by a high coverage of newborn visits. Reducing infant mortality is currently not up to par, so the quality of newborn care visits should be investigated more closely. The purpose of this study was to determine the quality of neonatal visit services at the Dolok Merawan Health Center, Serdang Bedagai Regency in terms of aspects of physical appearance (tangible), reliability (reliability), ability to understand (emphaty), responsiveness (responsiveness), and assurance of certainty (assurance). This research is a qualitative research with a phenomenological approach. Data collection was carried out in the form of observations, interviews, and focus group discussions (FGD) using the analytical technique. The results of the research conducted provide a statement that the quality of neonatal visit services has not run optimally. Of the five dimensions of service quality, there are four (4) service dimensions that are not optimal in supporting patient satisfaction. These four things are the midwife did not prepare a complete examination and only weighed, measured the temperature and recorded it in the visit book; midwives do not always make complete neonatal visits, lack of time for neonatal visit services, midwives rush to explain their illness, cramped neonatal visit service rooms where examination rooms are not separated from one another, and inadequate waiting rooms. Suggestions for institutions related to chair facilities in the waiting room are added to review and collect data on tools and facilities at the Puskesmas to procure or add and improve professionalism in carrying out neonatal visits.