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All Journal Pharmaciana: Jurnal Kefarmasian
Baroroh, Farida
Fakultas Farmasi UAD
Medicine & Pharmacology

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UJI EFEK ANTIHIPERGLIKEMIK EKSTRAK ETANOL DAUN KACAPIRING (Gardenia augusta, Merr) PADA TIKUS PUTIH JANTAN GALUR WISTAR Baroroh, Farida; Aznam, Nurfina; Susanti, Hari
Pharmaciana Vol 1, No 1 (2011): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (112.298 KB) | DOI: 10.12928/pharmaciana.v1i1.515

Abstract

Kacapiring leaf (Gardenia augusta Merr.) was often used in traditional drugs fortreatment diabetes mellitus. This research aim to know the antihiperglycemic effectethanolic extract of kacapiring leaf on white rats male strain of Wistar and how muchantihiperglycemic effect compared with glibenklamid. This study used oral glucosetolerance test method with loading glucose 4,5 g/kgW. Tested animal where 24 whitemale rats strain of Wistar age 2-3 months with weight 180-250 gram, devided into 4groups, each groups consist of 6 rats. Group I was as negative control group givenCMC-Na 1%, group II was as positive control group given glibenklamid dose 1,35mg/kgBB, group III and IV where given ethanolic extract of kacapiring leaf dose 500mg/kgBB and 250 mg/kgBB. Glibenklamid and exstract are given orally 60 minutesbefore glucose. Blood was taken from orbitalis sinus at minute (-90), (-60), 0, 30, 60,120, 180, 240, and 300. Blood glucose level was determined with GOD PAP enzymaticmethod, absorbance was observed using spectrophotometer at 500 nm. The result of thestudy was performed by giving ethanolic extract of kacapiring leaf dose 500 mg/kgWand 250 mg/kgW had antihiperglycemic effect. Ethanolic extract of kacapiring leaf dose500 mg/kgW and 250 mg/kgW could reduce blood glucoce level 58,97% and 80,60%compared with glibenklamid dose 1,35 mg/kgW could reduce blood glucoce level73,93%.
EVALUASI IMPLEMENTASI PELAYANAN INFORMASI OBAT PASIEN RAWAT JALAN DI INSTALASI FARMASI RUMAH SAKIT YOGYAKARTA Baroroh, Farida
Pharmaciana Vol 1, No 2 (2011): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (62.508 KB) | DOI: 10.12928/pharmaciana.v1i2.526

Abstract

To support high quality health service in hospital, Pharmacy Installation ofYogyakarta Hospital needs to evaluate implementation of drug information service foroutpatient. This study is aimed to identify the realization of drug information service ofoutpatient implementation of Pharmacy Installation of Yogyakarta Hospital comparedto the specified target. This study was carried out by descriptive design using secondarydata of Pharmacy Installation programs, interview with a pharmacist was assignedoutpatients serving as research subjects, as well as direct observation of druginformation service for outpatient. Gap analysis was used to identify the comparisonbetween the realization and specified target. The result of this study of evaluation indrug information service implementation of outpatient showed negative gaps as muchas -0.67%. The component information presented included the efficacy of drugs, how touse, the rules of use, duration of drug use, drug side effects, however the components ofdrug information that is unallowed in Pharmacy Installation of Yogyakarta Hospitalhow shcedule of drug use and signs toxicity.
Co-Authors Aznam, Nurfina Hari Susanti