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Irina, Sinta
Departement of Anesthesiology and Intensive Care Dr. Hasan Sadikin Hospital Bandung
Library & Information Science Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Perdarahan Epidural Spontan Akut pada Kombinasi Terapi Rivaroxaban, Clopidogrel dan Lumbrokinase Irina, Sinta; Umar, Nazaruddin; Arifin, Hasanul; Rehatta, Nancy Margareta; Saleh, Siti Chasnak
Jurnal Neuroanestesi Indonesia Vol 5, No 2 (2016)
Publisher : Departement of Anesthesiology and Intensive Care Dr. Hasan Sadikin Hospital Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v5i2.69

Abstract

Perdarahan intrakranial spontan pada terapi antikoagulan rivaroxaban mulai sering ditemukan, apalagi bila dikombinasi dengan antiplatelet clopidogrel maupun fibrinolitik lumbrokinase merupakan hal yang sering ditemukan pada penderita trombosis. Perdarahan intrakranial spontan terbanyak adalah perdarahan intracerebral. Perdarahan spontan epidural (EDH) akut merupakan hal yang jarang ditemukan, biasanya terjadi karena ada penyakit yang mendasarinya. Penatalaksanaan pada kasus ini berdasarkan patofisiologinya dan melibatkan multidisiplin ilmu lainnya. Seorang laki-laki, 26 tahun berat badan 80 kg yang didiagnosa deep vein thrombosis (DVT) mengalami penurunan kesadaran mendadak, pupil anisokor 4 mm/1mm ketika sedang beraktivitas. Tidak dijumpai riwayat cedera kepala. Setelah diresusitasi didapatkan hasil head CT-scan dengan EDH temporoparietal dextra 50 cc, dilakukan dekompresi craniektomi dan evakuasi EDH. Setelah 10 jam pasca operasi terjadi gejolak hemodinamik dan dilakukan head CT-scan ulang dan didapatkan EDH 80 cc dan minimal perdarahan intracerebral. Dilakukan redo craniektomi. Pasca operasi dirawat di ICU dengan koreksi faktor koagulasi. Pasien kembali komposmentis GCS 15 dengan gejala sisa hemiparese sinistra sementara.Acute Spontaneus Epidural Hemorrhage due to Combination Therapy Rivaroxaban, Clopidogrel and LumbrokinaseSpontaneous intracranial hemorrhage on anticoagulant therapy rivaroxaban lately often found, especially when combined with clopidogrel antiplatelet or fibrinolytic lumbrokinase is often found in patients with thrombosis. Spontaneous intracranial hemorrhage is most widely occured is intracerebral hemmorrhage. Spontaneous epidural hemorrhage (EDH) acute is a uncommon, usually occur because there is an underlying disease. Treatment on the case based on patophysiology and involves a multidisciplinary peer other sciences. A young man, 26 years old weight 80 kg which was diagnosed with deep vein thrombosis (DVT) awareness of sudden decline, the pupil anisokor 4 mm/1mm while activity. No head trauma history. After resuscitation, head Ct-scan with EDH temporoparietal dextra 50 cc, carried out the evacuation EDH and decompression craniektomi. After 10 hours of post-operative haemodynamic turmoil happened and done a head ct-scan and obtained EDH 80 cc and minimal intracerebral hemorrhage. Do redo craniektomi. Post-operative hospitalized in ICU with correction factor for coagulation. The patient recovers conciousness into composmentis GCS 15 with sequelae hemiparese sinistra temporary.
Ventilasi Mekanik yang Memanjang pada Pasien Cedera Otak Traumatik Berat dengan Kejang Pascatrauma Irina, Sinta; Oetoro, Bambang J; Gaus, Syafruddin
Jurnal Neuroanestesi Indonesia Vol 7, No 2 (2018)
Publisher : Departement of Anesthesiology and Intensive Care Dr. Hasan Sadikin Hospital Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v7i2.7

Abstract

Cedera kepala trauma masih merupakan masalah di seluruh dunia karena masih merupakan salah satu penyebab utama kematian dan kecacatan pada anak-anak dan dewasa. Akibat cedera primer bisa terjadi cedera sekunder yang akan mempengaruhi hasil luaran. Kejang merupakan salah satu komplikasi dari cedera kepala trauma berat. Kejadian kejang, demam, infeksi paru merupakan cedera sekunder yang akan mempengaruhi hasil luaran. Seorang laki-laki, 24 tahun, 50 kg dirujuk dari RSUD dengan penurunan kesadaran GCS E1M2V1, dari hasil scan kepala didapatkan  perdarahan intraserebral di frontal kanan/kiri dan parietal kanan, perdurahan subdural, perdarahan subarachnoid dan oedema serebri. Pasien segera diintubasi di UGD dan direncanakan evakuasi perdarahan dan dekompresi craniektomi. Setelah perawatan ke-2 pasien mengalami kejang yang cukup sering dan durasi lama sehingga proses penyapihan dari ventilator terhambat. Dan salah satu komplikasi pemakaian ventilator >48-72 jam adalah ventilator-associated pneumonia (VAP). Diberikan terapi antibiotik sesuai kultur dan penanganan bagi pemulihan paru. Pasien bisa lepas dari ventilator walaupun masih terpasang dengan tracheostomy.Prolonged of Mechanical Ventilation at Intensive Care Unit (ICU) in Patients with Severe Traumatic Head Injury with Post Traumatic SeizuresTraumatic head injury is still a worldwide problem as it is still one of the leading causes of death and disability in children and adults. As a result of a primary injury, a secondary injury will affect the outcome. Seizures are one of the complications of severe trauma head injury. Occurrence of seizures, fever, lung infections is a secondary injury that will affect the outcome. A man, 24 years old, 50 kg was referred from the RSUD with decreased awareness of GCS E1M2V1, from head scans obtained intracerebral hemorrhage on the right and left frontal and right parietal, subdural suburural, subarachnoid hemorrhage and cerebral edema. Patients are immediately intubated in the ER and planned evacuation of bleeding and craniectomy decompression. After the 2nd treatment the patient experienced frequent seizures and long duration so that the weaning process of the ventilator is inhibited. And one of the complications of ventilator use> 48-72 hours is VAP (ventilator-associated pneumonia). Given appropriate antibiotic therapy for culture and treatment for lung recovery. Patients can escape from the ventilator although still attached with tracheostomy. 
Co-Authors Hasanul Arifin Oetoro, Bambang J Rehatta, Nancy Margareta Saleh, Siti Chasnak Syafruddin Gaus Umar, Nazaruddin