Abstract: Stroke is an acute nerve disorder caused by circulatory disorders to the brain. The impact that often occurs in stroke patients is constipation due to disease complications, drugs and lack of mobiliza- tion. The purpose of this researchwas to analyze the effect of early mobilization sim right left to consti- pation in patients with Stroke Infarction in ICU Hospital dr. H. Mohammad Anwar Sumenep. The design of this research was quasy experiment with non-equivalent control group design. The population in this study wwa Stroke Infarct patients treated in ICU Hospital dr. H. Moh. Anwar Sumenep in August - September 2016 as many as 20 people, with a sample size of 10 people control group and 10 treatment groups. The research instruments are Standard Operating Procedure (SOP) of mobilization, check list and observation sheet. The data analysis used Chi square test with  (0,05). The results of the control group during pre test showed that all respondents (100%) were not defective and at the time of post test it was found that almost all (80%) of the respondents had defecation. While the results in the treatment group during pre test found that all respondents (100%) did not defecate and at the time of post test most (70%) of respondents experienced defecation. The result of data analysis showed that p value = 0,025 with  = 0,05 so that p value