<![CDATA[Background: Pomegranate bark (Punica granatum, L) contains ellagitannin, triterpenoid, alkaloids consisting of pelletierine, methylpelletieren, pseudopelletierine, flavonoids, and saponins. Substances that are able to inhibit bacterial growth are saponins and flavonoids. Objective: to determine the antibacterial activity of ethanol extract of pomegranate bark (Punicagranatum, L) on the Staphylococcus aureus bacteria. Method: The manufacture of pomegranate bark extract was carried out using the Soxlhetasi method, after extracting the antibacterial activity was carried out by using a cylinder diffusion method. Result: Ethanol extract of pomegranate bark (Punica granatum, L) has antibacterial activity against Staphylococcus aureus bacteria at a concentration of 10% b / v, 25% b / v, 50% b / v and 75% b / v with each inhibition zone diameter -as equal to 18.70 mm, 21.00 mm, 22.30 mm and 26.20 mm. Stastically, ethanol extract of pomegranate bark (Punica granatum, L) has significant antibacterial power with p = 0.001 (p <0.05). Conclusion: Ethanol extract of pomegranate bark (Punica granatum, L) has antibacterial activity against Staphylococcus aureus bacteria with very strong concentration is a concentration of 25% b / v, 50% b / v and 75% b / v, because the inhibition zone is> 20 mm.]]>
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