Jurnal Biologi Udayana
Vol 23 No 2 (2019): JURNAL BIOLOGI UDAYANA

Efek ekstrak etanol kedelai hitam (Glycine soja) terhadap ketebalan dermis mencit (Mus musculus L.) pasca unilateral ovariektomi

Isna Kurotul Akyun (Jurusan Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Jember (UNEJ) Jl. Kalimantan No.37, Krajan Timur, Sumbersari, Kec. Sumbersari, Kabupaten Jember, Jawa Timur 68121)
Susantin Fajariyah (Jurusan Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Jember (UNEJ) Jl. Kalimantan No.37, Krajan Timur, Sumbersari, Kec. Sumbersari, Kabupaten Jember, Jawa Timur 68121)
Mahriani Mahriani (Jurusan Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Jember (UNEJ) Jl. Kalimantan No.37, Krajan Timur, Sumbersari, Kec. Sumbersari, Kabupaten Jember, Jawa Timur 68121)

Article Info

Publish Date
30 Dec 2019

Abstract

Estrogen is a steroid hormone produced by the ovaries. Estrogen is a hormone that triggers collagensynthesis by fibroblast.Collagen has affects for thickness of dermis.Estrogen deficiency can lead disruptioncollagen synthesis, so has an impact on decline dermis thickness. Unilateral ovariectomy is the act ofremoval of one ovary in the female reproductive system and is a model for estrogen deficiency. Thecondition of estrogen deficiency can be overcome by giving phytoestrogens. Black soybean seed is one ofphytoestrogens source. The purpose of this study was to determine the effect of black soybean extract afterovariectomy on increasing on dermis thickness (Mus musculus L.). The dosage of black soybean ethanolextract used was 0.31 g / ml / day and 0.63 g / ml / day administered orally (gavage) for 20 days. The resultsshowed a dose of 0.31 g / ml / day may and 0.63 g / ml / day increase dermis thickness of mice.

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Journal Info
Jurnal Biologi Udayana
Website

Abbrev

BIO

Publisher

Universitas Udayana

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology

Description

Jurnal Biologi Udayana (p-ISSN 1410-5292 | e-ISSN 2599-2856 | DOI 10.24843/jbiounud) managed by the Department of Biology, Udayana University, published in two formats namely print and online regularly twice a year (June and ...