Jurnal Ilmu Dasar
Vol 10 No 2 (2009)

Effect of Hyperglikemic Conditions on Ovarian Structure and Estrous Cycle of Mice (Mus musculus L)

Eva Tyas Utami (Jurusan Biologi FMIPA Universitas Jember)

Article Info

Publish Date
02 Jul 2009

Abstract

Streptozotocin cause hyperglycemic condition in mice. The objective of this study was to determine whether the hyperglycemic conditioned by streptozotocin (STZ) has an impact at folicullar atretic and estrous cycle prolonged. Mice were injected by STZ until hyperglycemic condition was reached. The vaginal smear was recorded daily for twice estrous cycle. Mice were sacrificed soon after the last vaginal smear observation. The ovary was removed, prepared by parafin method and stained by hematoxylin-eosin.The result showed that hyperglycemic causes increasing the number of atretic follicles, decreasing the number of corpus luteum and prolonged of estrous cycle.

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Journal Info
Jurnal Ilmu Dasar
Website

Abbrev

JID

Publisher

Universitas Jember

Subject

Control & Systems Engineering Mathematics

Description

Jurnal ILMU DASAR (JID) is a national peer-reviewed and open access journal that publishes research papers encompasses all aspects of natural sciences including Mathematics, Physics, Chemistry and Biology. JID publishes 2 issues in 1 volume per year. First published, volume 1 issue 1, in January ...