Garuda - Garba Rujukan Digital

MIMBAR (Jurnal Sosial dan Pembangunan)

Volume 24, No. 1, Year 2008

Suwendar Suwendar (Program Studi Farmasi, Fakultas MIPA Universitas Islam Bandung (S1 – Akreditasi C/2015))
Bertha Rusdi (Program Studi Farmasi, Fakultas MIPA Universitas Islam Bandung (S1 – Akreditasi C/2015))
Kiki Mulkiya Yuliawati (Program Studi Farmasi, Fakultas MIPA Universitas Islam Bandung (S1 – Akreditasi C/2015))

Publish Date
17 Jun 2008

Anti thrombocytopenia activity of the Citrus aurantifolia fruit juice using direct counting methods on adrenaline-induced mice has been carried out. The induction effect tests of chloramphenicol, phenylbutazone and adrenaline were studied. Results showed that adrenaline at the dosage of 0.08 mg/ kg body weight given intravenously, gave thrombocytopenia effect after 9 and 12 minutes. Anti thrombocytopenia effect of the juice of Citrus aurantifolia fruit given orally into mice induced by adrenaline has been studied. Results showed that the juice of Citrus aurantifolia fruit at the dosage of 18 ml / kg of body weight during seven days increased the thrombocyte count significantly (P<0.05). The juice at 9 and 4,5 ml / kg of body weight inhibited the decrease of trombocyte count.

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