Paediatrica Indonesiana
Vol 22 No 9-10 (1982): September - October 1982

Effects of Chloramphenicol on the Titer of Widal in Typhoid Fever

Hafni Z. Soesilo (Department of Child Health, Gadjah Mada University Medical School, Yogyakarta, Central Java)
Yati Soenarto (Department of Child Health, Gadjah Mada University Medical School, Yogyakarta, Central Java)
Soelistyowati Soelistyowati (Department of Child Health, Gadjah Mada University Medical School, Yogyakarta, Central Java)
Ristanto Ristanto (Department of Microbiology, Gadjah Mada University Medical School, Yogyakarta, Central Java)
Ismangoen Ismangoen (Department of Child Health, Gadjah Mada University Medical School, Yogyakarta, Central Java)



Article Info

Publish Date
30 Oct 1982

Abstract

A study was camled out on 93 cases of Typhuid fever admitted to the Department of Child Health, Gadjah Mada University Hospital in Yogyakarta.The diagnosis is based on the discovery of Salnwnella typhi in the blood.It is stated that Chloramphenicol pos3esses an immunosuppressive nature ruppressing the titer of antibodies.Chloramphenicol has been administered with a dosagre of 75 mg/kg bodywelght/day.Checking on the titer of Widal war done weekly, beginning with the first week (prior to treatment with Chloramphenicol), larting four weeks (up to approximaJelyone or two weeks after Chlorampheru'col administration was stopped).ln only 91 of 93 cases follow up war possible: the W.idal titer incrt!OSed in 29 cases (31.9%), decreased in 23 (25.i%) cases and was constant in 39 cases (42.9%).

Copyrights © 1982






Journal Info

Abbrev

paediatrica-indonesiana

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of ...