Paediatrica Indonesiana
Vol 59 No 4 (2019): July 2019

Growth of HIV-exposed infants from birth to 6 months in the prevention of mother-to-child transmission program

Maria Priskila (Department of Child Health, Medical Faculty of Udayana University)
Ketut Dewi Kumarawati (Department of Child Health, Universitas Udayana Medical School/Sanglah Hospital, Denpasar, Bali)
Ni Putu Siadi Purniti (Department of Child Health, Universitas Udayana Medical School/Sanglah Hospital, Denpasar, Bali)



Article Info

Publish Date
24 Jul 2019

Abstract

Background Human immunodeficiency virus (HIV) infection is a global health issue. Most cases of HIV infection in children are acquired through transmission from HIV-infected mothers. Maternal HIV infection affects infant growth. Objective To evaluate the first six months of growth in HIV-exposed infants born to mothers in the prevention of mother-to-child transmission (PMTCT) program. Methods This prospective cohort study was done in 40 HIV-exposed infants born in Sanglah General Hospital, Bali. Subjects' underwent weight and length measurements at birth and monthly for 6 months. Data analyses used were repeated ANOVA test with Bonferonni post-hoc analysis for normally distributed data and Friedman test with Wilcoxon post-hoc analysis for abnormally distributed data. Correlations between birth weight and length to weight and length at 6 months of age were analyzed with Spearman's test. Results Subjects' mean birth weight was 2,900 (SD 546) grams and median birth length was 48 (range 36-52) cm. Subjects' body weight and length increased monthly throughout the measurement period (P<0.001). There was a strong negative correlation between birth weight and infant weight gain at 6 months of age (r=-0.678), and a moderate negative correlation between birth length and infant length gain at 6 months of age (r=-0.564). Conclusion HIV-exposed infants born to mothers in the PMTCT program have a significant body weight and body length growth in the first 6 months of life, and followed general WHO weight and length curves for age.

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Journal Info

Abbrev

paediatrica-indonesiana

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of ...