Medical and Health Science Journal
Vol 3 No 1 (2019): FEBRUARY

IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA

Meidyta Sinantryana Widyaswari (Universitas Nahdlatul Ulama Surabaya)
Hans Lumintang (Universitas Nahdlatul Ulama Surabaya)
Troef Soemarno (Universitas Airlangga)



Article Info

Publish Date
28 Feb 2019

Abstract

Background: Condylomata Acuminata (CA) is a sexually transmitted disease caused by the Human Papilloma Virus (HPV) type-specific and may be simultaneously co-infected with other HPV types associated with malignancy. Purpose: To differentiate between CA and histopathological of malignancy by immunohistochemistry. LiteratureReview: CA refers to benign epidermal proliferation caused by the HPV types 6 and 11, but co-infection with high- risk HPV types are common. The clinical presentation of CA can’t differentiate between benign or preneoplastik diplasia lesions. Koilocytes considered pathognomonic for HPV lesions, these findings sometimes don’t appear on CA, and histopathology was not accurate, that immunohistochemistry with MIB-1 (Ki-67) and p16 can beused. Conclusion: Immunohistochemistry examination can help differentiate the diagnosis between malignancy or non- malignancy in the case of CA.

Copyrights © 2019






Journal Info

Abbrev

MHSJ

Publisher

Subject

Health Professions Social Sciences

Description

Medical and Health Science (MHSJ) published peer-reviewed original articles research, case report or article review. This journal is published twice (February and August) by Faculty of Medicine Universitas Nahdlatul Ulama ...