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Medical and Health Science Journal
Published by Universitas Nahdlatul Ulama Surabaya
ISSN : 25497588     EISSN : 25497596     DOI : https://doi.org/10.33086/mhsj
Core Subject : Health, Social,
Health Professions Social Sciences
Medical and Health Science (MHSJ) published peer-reviewed original articles research, case report or article review. This journal is published twice (February and August) by Faculty of Medicine Universitas Nahdlatul Ulama Surabaya.
Arjuna Subject : -
Articles 155 Documents
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THE DIFFERENT EFFECTS OF ZINC SUPPLEMENT AND VELVET BEAN MUCUNA PRURIENS EXTRACTS TOWARD FERTILITY OF BALBC/ MICE Kurniasanti, Pradipta Pradipta; Rahfiludin, M Zen; Winarni, Sri
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 2 (2018): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i2.582

Abstract

Abstract: Good quality velvet beans and zinc supplement are well studied and known as rich source ofaphrodisiac. The following reseach was carried out to study the difference effect of zinc supplement (ZS)and velvet bean extracts (VBE) towards fertility of BALB/c mice i.e the number of sperm, the motility ofsperm, the viability of sperm, the morphology of sperm, the existence of vagina plug, and the birthcondition of mice. This study was an experiment using Posttest Only Controlled Group Design with threegroups. The first group (A1) as control, the second group (A2) receives subcutaneous injection of 2-methoxyethanol fraction as much as 200 mg/kg weight/day for 5 days, followed with ZS at a dosage of0,026 mg/day/head, and the third group (A3) receives subcutaneous injection of 2-methoxyethanolfraction as much as 200 mg/kg weight/day for 5 days, followed with VBE at a dosage of 56 mg/kg weight/day for 30 days. The quality of spermatozoa of A1, A2, and A3 was significant difference (p < 0.05).Both of A2 and A3 were no significant difference of mean number of sperm (p = 0.274), mean percentageof sperm motility (p = 0.739), mean percentage of sperm viability (p = 0.141) and mean value ofmorphology of sperm (p = 0.394). The quality of spermatozoa and the total number of baby mice livedand died of A1, A2 and A3 were significant difference. In addition, there was no significant differencein the existence of female mice's vaginal plug of A1, A2 and A3. This study showed that ZS and VBE canincrease the quality of spermatozoa of BALB/C mice.
GAMBARAN HISTOPATOLOGI PARU TIKUS WISTAR SETELAH DIBERI PAPARAN ASAP ROKOK Herdiani, Novera; Putri, Endah Budi Permana
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 2 (2018): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i2.583

Abstract

Abstract: Cigarette smoke is the main cause of lung obstruction. One of the obstructions in real that iscaused by cigarette smoke is oxidative stress. Oxidative stress trigger inflammation response occur andlung obstruction. Cigarette smoke able to cause lung histopathology changes like lungs obstruction onalveolus wall. Red dragon fruit extract tackle free radical then able to against the oxidative stress. Theobjective of this study to examines the image of rat lung histopathology under exposed cigarette smoke.Twenty four Wistar rats divided four groups: negative control, positive control, red dragon fruit extracttreatment of 7,2 g/200 g WB, and red dragon fruit extract10,8 g/200 g WB. Negative control only givenstandard feed. Positive control given standar feed and exposed 21 cigarette per day. Treatment groupgiven feed during 21 days. In the 22nd day rats be sacrificed, the lung taken out for observation andimage of rat lung histopathology changes by making lung organ histopathology preparationhematoxicillin Eosion (HE) staining and observed under magnification light microscope 400x. The endresult of the study indicate the finding of changes in lung histopathology such as obstruction level overthe lung tissue higher, alveolar macrophage covered alveoli after being exposed cigarette smoke. Groupwhich does not exposed cigarette smoke, lung alveolus macrophage in normal condition, there are noobstruction or alveolus macrophage occurred, its alveolar macrophage does no covering alveoli.Treatment group administered fruit dragon extract dose 10,8 g/200 g WB and dose 7,2 g/200 g WB seemalmost the same with negative control treatment. Conclusion of the research is cigarette smoke exposecan influence the number of alveolar macrophage on wistar rats. Suggestion very required furtherresearch on oxdative stress parameter.
DEPIGMENTING AGENT MELANOTOKSIK PADA PENGOBATAN MELASMA Putri, Winawati Eka; Kurniawati, Yuli; Djauhari, Tantawi
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 2 (2018): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i2.584

Abstract

Abstract: Human skin color is determined by melanin pigment,either eumelanin or feomelanin.Melanogenesis is a melanin synthesized process that is initiated with tirosin oxidation to DOPAquinoneby tirosinase, and then auto-oxidation to DOPA and DOPAchrome. Eumelanin are formed fromDOPAchrome, while pheomelanin from DOPAquinone with the presence of cysteine or gluthathione.Hyperpigmentation disorders like melasma, are difficult to treat especially in dark skinned individuals.Treatment of melasma can be topical or physical. Topical agent can use depigmenting agent, eitherindividual or combination with other. Depigmenting agent can be melanotoxic or toxic to melanocytewhich can be cell killing or cell damage. Hydroquinone, monomethyl of hydroqunone, N-acetyl-4-Scysteaminylphenol ,and azelaic acid are depigmenting agents melanotoxic. Majority of those agents actas tirosinase inhibitors which cause deactivation of tirosinase. The use of those agents in combinationare better to minimalize side effect of agents.
PADA HUBUNGAN ANTARA PERSEPSI, JENIS KELAMIN, STATUS TEMPAT TINGGAL, STATUS ORANG TUA DENGAN PERILAKU PENYALAHGUNAAAN NAPZA PADA KELAS XI DI SMK DARUL HUDA SIDOARJO Wardani, Erika Martining; Septianingrum, Yurike
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 2 (2018): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i2.586

Abstract

Abstract: Adolescence signify of transition from childhood to adulthood is easy to having psychologyand behavior problems, such as learning difficulty, anxiety, and drug addiction. School children asvulnerable group in drugs abuse behavior. The impact of drug abuse particularly alternately needle useget risk infection disease such as hepatitis B, C, and HIV. The objective of this research to examines thecorrelation between perception, sex, domicile status, parent status with drugs abuse behavior. This studyused cross sectional analytical design with simple random sampling technique. Population of theresearch are students of 155 individuals, sample with 50 respondents. Data analysis employed chisquare test. The result indicates that 83,7% having drugs abuse behavior with statistic test found thereare no correlation between perception ( value = 0,826) and drugs abuse behavior, and foundcorrelation between sex ( value = 0,001), domicile status relationship ( value = 0,001),parent statusrelationship ( value = 0,025), with drugs abuse behavior. Good communication among familymembers able to providing protection to child in order to avoid from drugs abuse. Good perceptionabout drugs, stay with complete parents and in harmony has correlation to drugs abuse prevention.
PENETUAN FORMULA UNTUK MENETAPKAN ESTIMASI KOLESTEROL-LDL Nugraha, Gilang; Edijanto, Soebagijoh Poegoeh
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 2 (2018): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i2.587

Abstract

Abstract: Measurement LDL-Cholesterol (LDL-C) can be performed by estimating LDL-C (cLDL-C) inthe blood. In addition to the first proposed Friedewald formula, several new formulas that promise betterexamination in determining LDL-C levels, proposed by Anandaraja, Puavilai, Chen, Vujovic, deCordova and Dansethakul. The subjects of the study were patients who performed routine lipid profileexamination in Institution of Clinical Pathology of Gedung Pusat Diagnostik Terpadu RSUD Dr.Soetomo Surabaya who performs 10 to 12 hours of fasting with TG less than 400 mg / dL. The sampleconsisted of 41 men and 48 women with an average age of 52 years. The statistical test on each cLDLC gave the Friedewald -1.32% bias value; Anandaraja -3,92%; Puavilai 4.26%, Chen -2.19%; Vujovic-23.65%; de Cordova -0.91% and Dansethakul 4.45%. The correlation coefficient on Friedewald0.9509; Anandaraja 0.9013; Puavilai 0.9576, Chen 0.9585; Vujovic 0.8745; de Cordova 0.9300 andDansethakul 0.9505. The proposed cLDL-C formula Chen et al promises in determining the LDL-Cestimate and the Vujovic formula gives a poor result in this study. Validation methods should be appliedto each of the cLDL formulas if they are to be applied to clinical laboratories.
KORELASI KADAR KOLESTEROL DENGAN KEJADIAN DIABETES MELLITUS TIPE 2 PADA LAKI-LAKI Anggraini, Rahayu
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 2 (2018): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i2.588

Abstract

Abstract: Type 2 diabetes is one of the most common chronic diseases in the world. It is estimated thatmore than 140 million people worldwide are currently suffering from diabetes, and by 2025, anestimated more than 300 million people will suffer from the disease. The purpose of this study was toevaluate the correlation of cholesterol with the incidence of Diabetes Mellitus disease. The type of thisresearch is observational with cross-sectional analytic approach and done in PLN employees, total are112 people of which are mens. All participants underwent biochemical analysis of fasting blood sugar(BSN) and 2 hours PP (post prandial), and total cholesterol level test. Determination of glucose byglucose oxidase method and cholesterol level by CHOD-PAP method. The mean results in normalcholesterol (< 200 mg/dl) obtained BSN = 73 mg / dl, 2 Hours PP = 92 mg / dl, and in abnormalcholesterol (> 200 mg/dl) mean BSN = 81 mg / dl, 2 hours PP = 109 mg / dl, in independent T test withp = 0001 in both groups of different cholesterol levels. Results of the Pearson's correlation test, therewas a significant positive correlation between GDP and cholesterol levels (r = 0.262, p = 0.005), and 2hours PP and cholesterol levels (r = 0.258, p = 0.006). Conclusions: There was a significant positivecorrelation between 2 hours PP and cholesterol levels. This study shows there is a correlation ofcholesterol levels that develop diabetes mellitus type 2.
HUBUNGAN ASUPAN ENERGI DAN ZAT GIZI DENGAN KEBUGARAN JANTUNG PARU SANTRI PONDOK PESANTREN AMANATUL UMMAH SURABAYA Amin, Nur; Lestari, Yanesti Nuravianda
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 1 (2018): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i1.590

Abstract

Abstrak: Olahraga merupakan salah satu bentuk usaha atau cara yang dilakukan oleh seseoranguntuk dapat meningkatkan derajat kesehatan. Dalam menjaga kesehatan, olahraga maupun aktivitasfisik yang dilakukan harus mampu melatih kebugaran jasmani seseorang. Kebugaran jasmani merupakan beberapa keterampilan dan status kesehatan seseorang yang dikaitkan dengan kemampuannyadalam melakukan aktivitas fisik sehari-hari. Salah satu komponen kebugaran jasmani yang berkaitandengan kesehatan adalah kebugaran jantung paru. Untuk mendapatkan kebugaran jasmani yang baikperlu adanya pemenuhan asupan makanan, istirahat, dan aktivitas fisik yang baik pula. Penelitianini bertujuan untuk mengetahui hubungan asupan energi dan zat gizi dengan kebugaran jantung parusantri Pondok Pesantren Amanatul Ummah Surabaya. Penelitian ini merupakan correlational descriptive dengan rancangan cross sectional dengan metode total sampling pada 20 santri PonpesAmanatul Ummah Surabaya yang duduk di kelas X dan XI Madrasah Aliyah. Instrumen pengambilandata menggunakan kuesioner semi-FFQ (Food Frequency Questionnaire) untuk mengetahui asupanenergi dan zat gizi dan multistage test untuk mengetahui VO2 maks. Hasil penelitian menunjukkantidak terdapat hubungan asupan energi dengan kebugaran jantung paru dengan nilai p=0,78 danhubungan asupan zat gizi (karbohidrat p=0,70, protein p=0,79, lemak p=0,69, natrium p=0,80,kalsium p=0,81, kalium p=0,93, magnesium p=0,31dan Fe p=0,29) dengan kebugaran jantungparu. Kesimpulannya, tidak terdapat hubungan asupan energi dan zat gizi dengan kebugaran jantungparu santri Amanatul Ummah Surabaya.
SURVEI KEPUASAN PASIEN KLINIK UIN SUNAN AMPEL Widayanti, Linda Prasetyaning
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 1 (2018): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i1.592

Abstract

Abstrak: Adanya mutu pelayanan yang sesuai dengan harapan pasien pasti membuahkan dampakpositif dalam keberlangsungan penyelenggaraan Klinik UINSA. Berdasarkan paparan di atas, makapenelitian ini bertujuan untuk menyurvei tingkat kepuasan pasien di Klinik UINSA. Penelitian inimerupakan penelitian yang bersifat survei. Sedangkan dari segi waktu, maka penelitian ini bersifatCross Sectional. Populasi penelitian ini adalah seluruh pasien Klinik UINSA periode bulan Mei2017. Sampling dilakukan dengan incidental sampling. Diperoleh sampel sebesar 30 pasien. Teknikpengambilan data dengan kuesioner. Hasil pengumpulan data disajikan dengan tabel distribusifrekuensi berupa grafik atau diagram. Hasil survey didapatkan bahwa karakteristik pasien 87%berusia kurang dari 20 tahun, 70% berjenis kelamin perempuan, 73% puas terhadap pelayananpetugas klinik, 87% puas terhadap pelayanan dokter klinik, 82% puas terhadap lama waktu registrasidi klinik, 73% puas terhadap lama waktu pelayanan apotek klinik, 90% puas terhadap kebersihanklinik. Diharapkan penelitian ini bisa dikembangkan oleh peneliti selanjutnya agar mutu pelayanandi Klinik UIN Sunan Ampel Surabaya bisa lebih baik.
TREND KASUS BARU INFEKSI HUMAN IMMUNODEFICIENCY VIRUS (HIV) DI INDONESIA PERIODE TAHUN 2012–2016 Adriansyah, Agus Aan; Firdausi, Nurul Jannatul
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 2 (2017): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i2.594

Abstract

Abstract: Countries in Southeast Asia have a very high HIV (
PEMBERIAN VCO (VIRGIN COCONUT OIL) PADA Tn. M DENGAN DIAGNOSIS MEDIS CVA INFARK DENGAN MASALAH KEPERAWATAN RISIKO KERUSAKAN INTEGRITAS KULIT DI RUANG ICU CENTRAL RUMKITAL dr. RAMELAN SURABAYA Setiyowati, Eppy
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 2 (2017): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i2.596

Abstract

Abstract: Ulcus decubitus is a serious dermal (skin) problem, especially for the unconscious patients with the lack of mobilization hospitalized in the ICU. It appears in the area which is localizedwith the necrotic tissues; it also usually appears on the surface of protruding bones, resulted fromthe long term pressure which increases the capillary pressure. This study was purposed to analyzethe effectiveness of the use of VCO to the patient with the risk of having ulcus decubitus in thecentral ICU of Rumkital Dr. Ramelan Surabaya (Surabaya Navy Hospital). The design used in thisstudy was case study done by investigating a problem through one case comprising of a single unit.The variable used in this study was the use of VCO to the patient with the risk of ulcus decubitus.The data were analyzed descriptively done by using inductive approach. The result of this studyconcludes that the use of VCO to Mr. M who has the risk of impaired skin integrity is effective toprevent decubitus.

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