Green Medical Journal
Vol 2 No 1 April (2020): Green Medical Journal

The Profile of Lung Adenocarcinoma Patients with Positive EGFR Mutation

Pandu Wiriansya, Edward (Unknown)
Ainun (Unknown)
Ratu, Puspa (Unknown)
Muhammad Reza Cesarian Noor, Andi (Unknown)



Article Info

Publish Date
04 Apr 2020

Abstract

Background: The high mortality rate in pulmonary carcinoma is a problem encountered in various countries, including Indonesia. According to WHO, there are 2.09 million people affected by lung cancer and 1.76 million deaths due to lung cancer worldwide. This study was aimed to determine the profile of lung adenocarcinoma patients with positive EGFR mutation. Methods: The study was descriptive study with cross-sectional approach using secondary data obtained from medical records of lung adenocarcinoma patients. Results: The present study revealed that lung adenocarcinoma was found higher in patients with age >40 years old (93.9%) compared to those with age <40 years old. It was also higher in male (66.7%) than in female patients. Most patient with lung adenocarcinoma were at the IIIB stage (42.4%). It was also reported that higher cases was found in patients with history of smoking more than 15 years (42.4%). Hemoptoe was the most reported clinical symptoms in patients with lung adenocarcinoma (87.9%). Lung adenocarcinoma was also observed higher in patients without family history of pulmonary adenocarcinoma (81.8%). Seventeen of 33 EGFR mutations (51.5%) were observed in exon 19 and fourteen (48.5%) were in exon 21. Conclusion: The most common EGFR mutation lung adenocarcinoma was observed in exon 19.

Copyrights © 2020






Journal Info

Abbrev

gmj

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

Description

Green Medical Journal (GMJ) is a peer-reviewed, open-access journal that publishes original research articles, review articles, and interesting case reports. The journal focuses on promoting medical and health sciences, derived from basic sciences, clinical and community health research, both in ...