Communications in Science and Technology
Vol 5 No 1 (2020)

Antifungal activity of microcapsule propolis from Tetragonula spp. to Candida albicans

Diah Kartika Pratami (Lab of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Pancasila University, South Jakarta, 12640, Indonesia)
Teti Indrawati (Faculty of Pharmacy, National Institute of Science and Technology (ISTN), South Jakarta, 12640, Indonesia)
Iis Istikomah (Faculty of Pharmacy, National Institute of Science and Technology (ISTN), South Jakarta, 12640, Indonesia)
Siti Farida (Department of Medical Pharmacy, Faculty of Medicine, Jakarta, 10430, Indonesia)
Paksi Pujianto (Department of Chemical Engineering, Faculty of Engineering, Depok, 16424, Universitas Indonesia)
Muhamad Sahlan (Department of Chemical Engineering, Faculty of Engineering, Depok, 16424, Universitas Indonesia)



Article Info

Publish Date
02 Jul 2020

Abstract

Propolis is a mixture of resin and saliva of Tetragonula spp. that have antifungal activity. The purpose of this study was to develop spray-dried microcapsule propolis (SDMP) and to analyze its antifungal activity to Candida albicans. The SDMP was obtained using a spray drying method by maltodextrin and gum arabic coating. The antifungal activity of SDMP of rough propolis (taken from the outside beehive) and smooth propolis (taken from the inside beehive) was analyzed. The macroscopic characterization showed that SDMP has a powder form with brownish-yellow color. The microscopic characterization showed SDMP has a spherical uniform particle shape with particle size 9.32 - 14.61 µm. The encapsulation efficiency of smooth and rough SDMP was 81.22% and 83.04%; moisture content 5.58% and 5.84%; water solubility 98.19% and 98.31%, respectively. The microbial inhibitory concentration to C. albicans was the diameter of 6.33±1.5 to 10±2.5 mm. SDMP displayed remarkable activity in the assays against C. albicans.

Copyrights © 2020






Journal Info

Abbrev

cst

Publisher

Subject

Engineering

Description

Communication in Science and Technology [p-ISSN 2502-9258 | e-ISSN 2502-9266] is an international open access journal devoted to various disciplines including social science, natural science, medicine, technology and engineering. CST publishes research articles, reviews and letters in all areas of ...