Dentika Dental Journal
Vol. 23 No. 1 (2020): Dentika Dental Journal

The Role of Porphyromonas gingivalis Virulence Factors in Periodontitis Immunopathogenesis: Peran Faktor Virulensi Porphyromonas Gingivalis pada Imunopatogenesis Periodontitis)

Septiwidyati, Tienneke Riana (Unknown)
Bachtiar, Endang Winiati (Unknown)

Article Info

Publish Date
07 Jul 2020

Abstract

Porphyromonas gingivalis is an anaerobic Gram-negative oral bacterium involved in the pathogenesis of periodontitis. Periodontitis is an infection that is characterized by damage to the supporting tissues of the teeth so that it can cause tooth loss if not given treatment. P. gingivalis locally can invade periodontal tissue and avoid host defense mechanisms. This bacterium has virulence factors which can cause deregulation of innate immune responses and inflammation in the host. The role of P. gingivalis virulence factors such as capsules, fimbriae, lipopolysaccharides, and gingipain in the pathogenesis of periodontitis will be discussed in this paper.

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Journal Info
Dentika Dental Journal
Website

Abbrev

dentika

Publisher

Universitas Sumatera Utara

Subject

Dentistry

Description

d e n t i k a DENTAL JOURNAL is one of the journals managed by TALENTA Universitas Sumatera Utara which first published in 2015. This is an online scientific journal that publishes articles and scientific work from Researches, Case Reports and Literature Reviews in Dentistry and Dental Science. The ...