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All Journal Dentika Dental Journal
Septiwidyati, Tienneke Riana
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Dentistry

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The Role of Porphyromonas gingivalis Virulence Factors in Periodontitis Immunopathogenesis: Peran Faktor Virulensi Porphyromonas Gingivalis pada Imunopatogenesis Periodontitis) Septiwidyati, Tienneke Riana; Bachtiar, Endang Winiati
Dentika: Dental Journal Vol. 23 No. 1 (2020): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (463.716 KB) | DOI: 10.32734/dentika.v23i1.3421

Abstract

Porphyromonas gingivalis is an anaerobic Gram-negative oral bacterium involved in the pathogenesis of periodontitis. Periodontitis is an infection that is characterized by damage to the supporting tissues of the teeth so that it can cause tooth loss if not given treatment. P. gingivalis locally can invade periodontal tissue and avoid host defense mechanisms. This bacterium has virulence factors which can cause deregulation of innate immune responses and inflammation in the host. The role of P. gingivalis virulence factors such as capsules, fimbriae, lipopolysaccharides, and gingipain in the pathogenesis of periodontitis will be discussed in this paper.
The Role of Porphyromonas gingivalis Virulence Factors in Periodontitis Immunopathogenesis: Peran Faktor Virulensi Porphyromonas Gingivalis pada Imunopatogenesis Periodontitis) Septiwidyati, Tienneke Riana; Bachtiar, Endang Winiati
Dentika: Dental Journal Vol. 23 No. 1 (2020): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (463.716 KB) | DOI: 10.32734/dentika.v23i1.3421

Abstract

Porphyromonas gingivalis is an anaerobic Gram-negative oral bacterium involved in the pathogenesis of periodontitis. Periodontitis is an infection that is characterized by damage to the supporting tissues of the teeth so that it can cause tooth loss if not given treatment. P. gingivalis locally can invade periodontal tissue and avoid host defense mechanisms. This bacterium has virulence factors which can cause deregulation of innate immune responses and inflammation in the host. The role of P. gingivalis virulence factors such as capsules, fimbriae, lipopolysaccharides, and gingipain in the pathogenesis of periodontitis will be discussed in this paper.
Co-Authors Endang Winiati Bachtiar