Red Galangal (Alpinia purpurata K. Schum) and turmeric (Curcuma Domestica Val.) plant are icluded in the Zingeberaceae family. The utilization of parts of red galangal and turmeric plants such as rhizomes can be used as medicine. The objective of research is to determine the antibacterial activity of red galangal and turmeric leaves extracts. Examination of simplicia characteristics include : macroscopic, microscopic examinations, determination of water content, determination of ash content. Phytochemical screening includes examination of classes of alkaloids, flavonoids, glycosides, saponins, tannins and steroids/triterpenoids. The extraction was done by maceration using 96% ethanol as solvent. The antibacterial activity by agar diffusion method to using paper discs against Escherichia coli and Staphylococcus aureusbacteria. Simplex characterization for red galangal dan turmeric were showed water level of red galangal is 4,73% and turmeric is 6,83%. Ash content of red galangal is 3,64% and turmeric is 5,45%. The results of phytochemical screening of red galangal is alkaloids, flavonoids, glycosides, saponins, tannins and steroids/triterpenoids. Turmeric is alkaloids, flavonoids, glycosides, saponins, tannins. The results of antibacterial activity test showed that there were antibacterial differences of leaf extract of red galangal ant turmeric leaves in which turmeric leaves were more effective against Escherichia coli and Staphyloccus aureus than red galangal.
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