Berkala Ilmiah Mahasiswa Farmasi
Vol 6 No 1 (2019): Berkala Ilmiah Mahasiswa Farmasi Indonesia (BIMFI)

FORMULASI GRANUL EFFERVESCENT DARI LIOFILISAT MAHKOTA BUNGA KASUMBA TURATE (Carthamus tinctorius Linn) SEBAGAI SUPLEMEN ANTIOKSIDAN ALAMI

Diana Astuti (Universitas Hasanuddin)
Yulfira Amalika (Universitas Hasanuddin)
Mochammad Hamzah Haz (Universitas Hasanuddin)



Article Info

Publish Date
30 Jun 2019

Abstract

Infection is the highest prevalence of disease in Indonesia. Efforts to increase the prevalence of infection is to improve the community's immune system. Kasumba turate is an endemic plant of South Sulawesi empirically used in the cure of smallpox and improve the nature of the body due to the nature of its imunomodulator. Traditional decoction of the Kasumba turate is less effective for consuming because it has a bitter taste, so the aim of this study is to modified decocta of kasumba turate becomes effervescent granules which is contain antioxidant to reducing free radicals in the body without reduce its usefulness. The method of making effervescent granule supplementation is by using infusa (decoction) from a lyophilized kasumba flower with Freeze Dryer and formulated with a combination of citric acid and sodium bicarbonate 1: 1.5. Effervescent granule preparationss were evaluated by LOD, MC, compressibility, species weight and pH test to obtain a qualified preparation and antioxidant analysis by DPPH method. Based on the evaluation of the preparation, it is found that the effervescent kasumba turate granule fulfill the applicable requirements: acid granules obtained% MC and% LOD 0.5% and 0.5%, basic granule% MC and% LOD 0.7%, 0.77%, flow properties break 27o, and flow rate 9.7 g/s),% compressibility 16% and weight type 1.66, pH of the preparation 7. The effervescent lyophilisate preparation of kasumba turate becomes an effective supplement in enhancing the immune system and as an antioxidant for all age.

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Journal Info

Abbrev

bimfi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Description

BIMFI is a peer-reviewed and open access journal that prioritize the publication manuscript of pharmaceutical and health cluster students. This journal publishes editorial, research article, reviews, evidence-based case report, and also interesting case reports/case study. BIMFI receives manuscripts ...