Chemistry Indonesian Journal of Chemical Research
Vol 2 No 1 (2014): Edisi Bulan Juli (Edition For July)

Synthesis Of 1-phenyl-4-(3’, 4’-dimethoxy phenyl)-1-Buten-3-on From Eugenol

Candra Y. Tahya (Department of Chemistry, Faculty of Mathematics and Natural Science, University of Pattimura-Indonesia)
Hanoch J. Sohilait (Department of Chemistry, Faculty of Mathematics and Natural Science, University of Pattimura-Indonesia)
Serly J. Sekewael (Department of Chemistry, Faculty of Mathematics and Natural Science, University of Pattimura-Indonesia)

Article Info

Publish Date
31 Jul 2014

Abstract

The synthesis of 1-phenyl-4-(3’, 4’-dimethoxy phenyl)-1-buten-3-one from eugenol has been done through four reaction steps. The metilation of eugenol with dimethyl sulphate yields 81.81% of methyl eugenol. Oxymercuration-demercuration of methyl eugenol with mercury acetate yields 67.27% of methyl eugenyl alcohol. Oxidation of methyl eugenyl alcohol with pyridinium chloro chromate (PCC) yields 45.31% of methyl eugenyl ketone. Aldol condensation reaction of methyl eugenyl ketone with benzaldehide catalyzed by potasium hydroxyde yields 7.38% of 1-phenyl4-(3’,4’-dimethoxyphenyl)-1-buten-3-one. The purity of compounds was tested by GC and LC. The Elucidation of structure was analyzed by FTIR, GC-MS, LC-ESI-MS, and H-NMR.

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Journal Info
Chemistry Indonesian Journal of Chemical Research
Website

Abbrev

Indonesian Journal of Chemical Research (Indones.

Publisher

Universitas Pattimura

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Engineering Environmental Science

Description

Indo. J. Chem. Res. is a journal that regularly publishes primary articles covering all branches of chemistry and its sub-disciplines. Published articles consist of complete research, short communication, and review articles. The scope of published articles is not limited to inorganic chemistry, ...