Jurnal Insan Farmasi Indonesia
Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia

ANALISIS EFEKTIVITAS PENGGUNAAN ANTIBIOTIKA PADA PASIEN SIROSIS HEPATIS DENGAN KOMPLIKASI SPONTANEOUS BACTERIAL PERITONITIS DI SALAH SATU RUMAH SAKIT DI YOGYAKARTA

Adnan Adnan (Universitas Ahmad Dahlan)
Lolita Lolita (Universitas Ahmad Dahlan)



Article Info

Publish Date
30 May 2020

Abstract

Cirrhosis is a diffusion process characterized by fibrosis and changes from normal hepatic structures to structurally abnormal nodules. In general, complications that often occur in hospitalized patients are Spontaneous Bacterial Peritonitis (SBP). Many antibiotic therapies can be used for SBP, for example aminoglycosides, third-generation cephalosporins, penicillins, quinolones and sulfa groups. The purpose of this study was to determine whether there are differences in the effectiveness of antibioics used in SBP therapy. This type of research is observational analytic with cross sectional approach. Retrospective data collection in patients with cirrhosis of the liver with SBP complications in PKU Muhammadiyah Yogyakarta Hospital in 2018. Samples are all patients with cirrhosis of the liver with SBP complications who meet the inclusion and exclusion criteria. The sampling method is purposive sampling. The data taken is demographic characteristic data and clinical characteristics. Analysis of the data used in this study is multivariate analysis and different tests. There were 30 samples that met the criteria with a composition of 18 men (60%) and 12 women (40%). There were 8 people who received ceftriaxone antibiotics and 22 people got cefotaxime therapy.

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Journal Info

Abbrev

JIFI

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics

Description

Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that ...