The Journal of Pure and Applied Chemistry Research
Vol 9, No 3 (2020): Edition September-December 2020

In vitro Clot Lysis Activity of Phenolic Compound Degrading Product From Lignin Sugarcane Baggase Using Ochrobactrum sp.

Arie Srihardyastuti (Chemistry Departement, Faculty of Mathematics and Natural Science, University of Brawijaya, JL.Veteran 65145 Malang - INDONESIA)
Moh Farid Rahman (Chemistry department, Brawijaya University)
Tri Ardyati (Biology department, Brawijaya University)
Anna Roosdiana (Chemistry department, Brawijaya University)
Indah Prihartini (Biotechnology Departement, Univeritas Muhammadiyah Malang)



Article Info

Publish Date
07 Oct 2020

Abstract

Sugarcane bagasse (Saccharum officinarum L) is a readily available waste product of cane sugar processing. The content of lignocelluloses in sugarcane bagasse is approximately 52.7% cellulose, 20% hemicelluloses, and 24.2% lignin. Lignin can be degraded enzymatically by using microorganisms, such as Ochrobactrum sp. Monomer derived from lignin degradation using these bacteria in the optimum condition of sugarcane fermentation (pH 6, temperature 40 °C, for 5 days of incubation, the concentrations of starter 29%) by GC-MS yielded phenolic compounds such as 4-methyl-2, 6-di-tert-butylphenol; 2,6-di-tert-butylquinone; phenol, and p-hydroxybenzaldehide. The thrombolytic activity of these lignin monomers can be tested in-vitro by measuring the ability of clot lysis. Lignin did not have in-vitro clot lysis activity, whereas the lignin monomers in filtrat of fermented sugarcane bagasse have an in-vitro clot lysis activity, although its capacity is not as high as streptokinase.

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Journal Info

Abbrev

jpacr

Publisher

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry Materials Science & Nanotechnology Medicine & Pharmacology

Description

The Journal of Pure and Applied Chemistry Research focuses in publishing research articles in the field of Chemistry and Applied Chemistry. The target is in exploring, investigating, and developing chemicals sources from local and/or Indonesian to increase the value. Scope of the journal is organic ...