VALENSI
Jurnal Kimia VALENSI Volume 6, No. 2, November 2020

A Cytotoxic Flavanone from The Pod Peels of Theprosia vogelii Hook.f.

Valentina Adimurti Kusumaningtyas (Department of Chemistry Faculty of Sains and Informatic Universitas Jenderal Achmad Yani)
Nia Sri Hardianti (Department of Chemistry Faculty of Sains and Informatic Universitas Jenderal Achmad Yani)
Melina Melina (Department of Informatics, Faculty of Science and Informatics, Universitas Jenderal Achmad Yani, Jalan Terusan Jenderal Sudirman, Cimahi 40285, Indonesia)
Lia Dewi Juliawaty (Natural Product Chemistry Group, Faculty of Mathematics and Natural Sciences, Institut Tenologi Bandung, Jalan Ganesha no. 10, Bandung 40132, Indonesia)
Yana Maolana Syah (Natural Product Chemistry Group, Faculty of Mathematics and Natural Sciences, Institut Tenologi Bandung, Jalan Ganesha no. 10, Bandung 40132, Indonesia)

Article Info

Publish Date
03 Dec 2020

Abstract

Tephrosia vogelii Hook.f. is a species of the family Fabaceae (Leguminoceae). These plants are termed ″Polong-polongan″ in Indonesia, and are known to contain active flavonoid groups. Previous studies have shown the isolation of one known flavanone: isolonchocarpin from methanol extract, and the structure obtained was established based on chemical evidence as well as spectroscopic methods, including NMR, and also by a comparison with published data. This research is aimed at evaluating the cytotoxic property of methanol extract against larvae of Arthemia salina Leach, using the Brine Shrimp Lethality Test (BSLT) method. The results show potent cytotoxicity at LC50 of 41.40 ppm.

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Journal Info
VALENSI
Website

Abbrev

valensi

Publisher

Universitas Islam Negeri Syarif Hidayatullah Jakarta

Subject

Chemistry

Description

Jurnal Kimia Valensi is a biannual and peer-reviewed open access journal published by Department of Chemistry, Faculty of Science and Technology UIN Syarif Hidayatullah Jakarta. This journal covering all aspect of ...