Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal)
Vol. 10 No. 2 (2021): November

Inflammation in Depression

Novi Agung Rahmawati (Department of Psychiatry Faculty of Medicine, Universitas Airlangga, Surabaya)
Azimatul Karimah (Department of Psychiatry, Faculty of Medicine, Universitas Airlangga-Dr.Soetomo General Academic Hospital, Surabaya,)
Mustafa M Amin (Department of Psychiatry, Faculty of Medicine, Universitas Sumatera Utara, Medan,)

Article Info

Publish Date
27 Sep 2021

Abstract

Depression is a chronic condition that imposes a substantial burden of disability globally. Three principal neurotransmitters (norepinephrine (NE), dopamine (DA), and serotonin (5-HT)) implicated the pathophysiology and treatment of depression. Clinical studies have found a significant association between numerous pro-inflammatory cytokines with depressive symptoms, endocrine, and neurotransmitter systems. Here, we detail our current understanding about the role of inflammation in depression, the mechanisms that are involved, and show how it is possible to innovate and develop new therapeutics of depression in the field of neuroinflammation.

Copyrights © 2021




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Journal Info
Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal)
Website

Abbrev

JPS

Publisher

Universitas Airlangga

Subject

Health Professions Medicine & Pharmacology

Description

Jurnal Psikiatri Surabaya (JPS) is a scientific publication every 6 months (semester). JPS accepts submissions in the form of original manuscripts, literature review, case reports, and editorials in Indonesian in the format of Enhanced Spelling or English in accordance with the scope of Psychology, ...