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All Journal Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal)
Novi Agung Rahmawati
Department of Psychiatry Faculty of Medicine, Universitas Airlangga, Surabaya
Health Professions Medicine & Pharmacology

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Inflammation in Depression Novi Agung Rahmawati; Azimatul Karimah; Mustafa M Amin
Jurnal Psikiatri Surabaya Vol. 10 No. 2 (2021): November
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v10i2.22045

Abstract

Depression is a chronic condition that imposes a substantial burden of disability globally. Three principal neurotransmitters (norepinephrine (NE), dopamine (DA), and serotonin (5-HT)) implicated the pathophysiology and treatment of depression. Clinical studies have found a significant association between numerous pro-inflammatory cytokines with depressive symptoms, endocrine, and neurotransmitter systems. Here, we detail our current understanding about the role of inflammation in depression, the mechanisms that are involved, and show how it is possible to innovate and develop new therapeutics of depression in the field of neuroinflammation.
Co-Authors Karimah, Azimatul Mustafa M Amin