Kesmas: Jurnal Kesehatan Masyarakat Nasional
Volume 13, Issue 3, February 2019

Influence of Decentralization and Type of Patient on Loss to Follow-up among Multidrug-Resistant Tuberculosis Patients in Indonesia from 2014 to 2015

Noerfitri Noerfitri (Department of Biostatistics and Population Study, Faculty of Public Health, Universitas Indonesia)
R. Sutiawan (Department of Biostatistics and Population Study, Faculty of Public Health, Universitas Indonesia)
Tri Yunis Miko Wahyono (2Department of Epidemiology, Faculty of Public Health, Universitas Indonesia)
Pratiwi Ayuningtyas Hartono (The Division of Human Nutrition and Health, Wageningen University and Research)



Article Info

Publish Date
04 Feb 2019

Abstract

Drug-resistant tuberculosis (TB) patients have a greater risk of loss to follow-up (LTFU) than drug-sensitive TB patients, due to their longer treatment duration. This study aimed to determine the influence of decentralization and patient type on LTFU among multidrug-resistant TB (MDR-TB) patients in Indonesia. A retrospective cohort study was conducted at all MDR-TB treatment healthcare facilities in Indonesia from  014 to 2015. Using total sampling technique, 961 patients were examined and sampled. Of these patients, 86.03% were decentralized. Patients were classified into types as follows: 35.17% were “relapse” patients, 5.52% were “new,” 13.94% were classified as “after LTFU” patients, 23.10% were “treatment failure category 1” patients, 20.29% were “treatment failure category 2” patients, and 1.90% were classified as “other types” patients. Decentralization reduced LTFU risk by up to 46% (HR = 0.54, 95% CI 0.35–0.84). LFTU in “after LTFU,” “treatment failure category 2,” and “other types” patients was higher by 50%, 53%, 74%, respectively compared to LFTU occurrence in “relapse” (baseline) patients. Among “treatment failure category 2 patients, female patients were 2.13 times more likely to have an occurrence of LFTU, while male patients were 0.55 times as likely to have an occurrence of LFTU, compared to “relapse” type patients of the same sex.

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Journal Info

Abbrev

kesmas

Publisher

Subject

Public Health

Description

Kesmas: National Public Health Journal is on public health as discipline and practices related to preventive and promotive measures to enhance health of the public through scientific approach applying variety of technique. This focus includes area and scope such as biostatistics, epidemiology, ...