IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)
Vol 6, No 3 (2021): October 2021

Alkaloids of Fagraea fragrans (Tembesu) Fruits

Dasril Basir (Department of Chemistry, University of Sriwijaya)
Miksusanti Miksusanti (Department of Chemistry, University of Sriwijaya)
Dian Dwita Maizur (Department of Chemistry, University of Sriwijaya)
Susilawati Susilawati (Department of Clinical Pathology, Faculty of Medicine, University of Sriwijaya)



Article Info

Publish Date
20 Oct 2021

Abstract

The aim of this paper is to visualize the alkaloids of Fagraea fragrans fruits therefore the fruits can be scientifically used as herb traditional medicines and phytocosmetics.  Three alkaloids have successfully been identified from those Fagraea fragrans fruits, Loganiaceae. They are gentialutine, gentianine, and isaindigotone. The alkaloids were alternately explored by means of ether and 2% H2SO4 extractions. The sulphuric acid phase was naturalized with ammonium chloride and then extracted with ethyl acetate. The residue were then subjected to silica gel G60 (70-230 mesh) column chromatography and eluted with 40% ethyl acetate in n-hexane. The LC-MS spectral of alkaloids gave the protonated molecular ion peaks at m/z (r.t. minute) = 150.08 (1.39), 176.06 (4.80), and 351.37 (5.24) respectively.

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Journal Info

Abbrev

IJFAC

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science

Description

Indonesian Journal of Fundamental and Applied Chemistry (IJFAC) is an international research journal and invites contributions of original research articles as well as review articles in several areas of chemistry. The journal aims to publish refereed, high-quality research papers with significant ...