KESANS : International Journal of Health and Science
Vol 1 No 2 (2021): KESANS : International Journal of Health and Science

Preliminary Study On Latent Membrane Protein-1 (LMP-1) And Bcl-2 Associated X (BAX) In Exosomes Of Patients With Nasopharingeal Cancer In NTB Provincial Hospital

Puput Angrayany Sapar (Universitas Mataram)
Hamsu Kadriyan (Universitas Mataram)
Didit Yudhanto (Universitas Mataram)

Article Info

Publish Date
20 Nov 2021

Abstract

Nasopharyngeal cancer is one of the most common types of cancer in Indonesia, especially head and neck cancer. One of the etiology of this cancer is infection with Epstein-Barr virus. Early diagnosis is difficult to establish because the early signs and symptoms of nasopharyngeal carcinoma are not specific. Examination of latent membrane protein-1 (LMP1) oncogene expression and BCL2-associated X (BAX) gene expression proved to be useful in the identification of nasopharyngeal cancer. LMP1 oncogene is an oncogene that functions as a tumor necrosis factor receptor (TNFR), so that apoptosis does not occur and promotes invasion and metastasis. The BAX gene is a pro-apoptotic gene that inhibits cancer development, but its regulation will be downregulated by LMP1 because LMP can protect B-cells from apoptosis.

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Journal Info
KESANS : International Journal of Health and Science
Website

Abbrev

kesans

Publisher

Cv.Rifainstitut

Subject

Chemistry Health Professions Medicine & Pharmacology Physics Public Health

Description

KESANS : International Journal of Health and Science provides a means for ongoing discussion of the relevant issues that fall within the focus and scope of the journal that can be examined empirically. This journal publishes research articles in the medicine, Nursing, Midwifery, Public Health, ...