Pharmacon
Vol 18, No 1 (2021)

Aktivitas Antihiperurisemia Ekstrak Etanol Daun Afrika (Vernonia amygdalina Delile.) pada Mencit Putih Galur Swiss Webster yang Diinduksi Melinjo dan Hati Ayam

Doni Anshar Nuari (Prodi Farmasi Fakultas MIPA Universitas Garut, Jl. Jati No.42B, Tarogong, Garut, Indonesia)
Hesti Renggana (Prodi Farmasi Fakultas MIPA Universitas Garut, Jl. Jati No.42B, Tarogong, Garut, Indonesia)
Cindra Tri Yuniar (Sekolah Farmasi Institut Teknologi Bandung, Jl. Ganesha No.10, Bandung, Indonesia)
Mentari Novitasari (Prodi Farmasi Fakultas MIPA Universitas Garut, Jl. Jati No.42B, Tarogong, Garut, Indonesia)
Asholeha Lulu (Prodi Farmasi Fakultas MIPA Universitas Garut, Jl. Jati No.42B, Tarogong, Garut, Indonesia)

Article Info

Publish Date
30 Jun 2021

Abstract

Hyperuricemic is a condition in which uric acid level in blood exceeds its normal level. Empirically, African leaves (Vernonia amygdalina Delile.) were used to treat diabetic, hypercholesterolemic, fever, hypertension and hyperuricemic by drinking boiled water of African leaves. This in vivo study was performed to determine antihyperuricemic activity of ethanolic extract of African leaves on male mice using the POCT (Point of Care Testing) method. Suspension combination of melinjo and chicken liver juice were used as hyperuricemic inductor. It is given orally for consecutive 9 days and the uric acid level were tested on day 1, 3, 6, and 9. The results showed that the ethanolic extract of African leaves (Vernonia amygdalina Delile.) at dosage 100, 200, and 400 mg/KgBW had a significantly different antihyperuricemic activity against negative control.

Copyrights © 2021




Citation Download
RIS
EndNote, Reference Manager, ProCite
BibTex
Latex, Jabref
Original Source
Download Original
Google Scholar
Check in Google Scholar
Journal Info
Pharmacon
Website

Abbrev

pharmacon

Publisher

Universitas Muhammadiyah Surakarta

Subject

Health Professions Medicine & Pharmacology

Description

Pharmacon: Jurnal Farmasi Indonesia is a collection of publication journals, covering all aspects of Pharmaceutical sciences, including Technology of Formulations, Excipients Optimization, Extract and Herbal Standardizations, Pharmacological activity determination on natural sources, Drug Synthesize ...