Majalah Obstetri dan Ginekologi
Vol. 29 No. 3 (2021): December

Association of age at menarche, parity, and hormonal contraceptive use with the histologic type of ovarian cancer

Firda Azizah (Midwifery Program, Faculty of Medicine, Universitas Airlangga, Surabaya)
Pungky Mulawardhana (Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya)
Willy Sandhika (Department of Pathology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya)



Article Info

Publish Date
25 Nov 2021

Abstract

HIGHLIGHT1. Relationship between age at menarche, parity, and contraceptive use with histologic type of ovarian cancer was analyzed. 2. A number of patients with ovarian cancer were analytically observed with retrospective cross-sectional approach and the histologic types of the cancer were determined.3. Age of menarche, parity, and hormonal contraceptive use was found not to have significant correlation with histologic type of ovarian cancer. ABSTRACTObjectives: This study analyzed the relationship between age at menarche, parity, and contraceptive use with histologic type of ovarian cancer.Materials and Methods: This study used an observational analytic with a retrospective cross-sectional approach. The research samples were 128 patients with ovarian cancer at Dr. Saiful Anwar Hospital, Malang, Indonesia, in 2017-2019. All patients underwent primary staging laparotomy. The histologic types of the ovarian cancer consisted of serous type as many as 45, mucinous 45, endometrioid 10, clear cell 20, and others 4. Data analysis used chi-square test.Results: The p value for the relationship between age of menarche and histologic type of ovarian cancer was p=0.500 (p> 0.05), parity p=0.313, and contraceptive use p=0.824. The distribution of clear cell was more common in multiparous, 40% of endometrioid found in nulliparous, while serous were more common in women with hormonal contraceptive use >5 years, whereas mucinous were more common in those with history of use of <5 years.Conclusion: There was no significant relationship between age of menarche, parity, and hormonal contraceptive use on  histologic type of ovarian cancer.

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Journal Info

Abbrev

MOG

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology ...