Indonesian Journal of Chemistry
Vol 21, No 6 (2021)

Electrogenerated Chemiluminescence for Immunoassay Applications

Isnaini Rahmawati (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Kampus UI, Depok 16424, Indonesia)
Irkham Irkham (Department of Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi 3-14-1, Yokohama, 223-8522, Japan)
Rahmat Wibowo (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Kampus UI, Depok 16424, Indonesia)
Jarnuzi Gunlazuardi (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Kampus UI, Depok 16424, Indonesia)
Yasuaki Einaga (Department of Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi 3-14-1, Yokohama, 223-8522, Japan)
Tribidasari Anggraningrum Ivandini (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Kampus UI, Depok 16424, Indonesia)



Article Info

Publish Date
27 Aug 2021

Abstract

Electrogenerated chemiluminescence (ECL) has recently become one of the most prominent and well-established transducers for immunoassay techniques. ECL relates a luminophore concentration in solution with the emission of light triggered by an electrochemical stimulus. ECL immunoassay (ECLIA) performance depends on the parameters of its light generation, including the luminophore, the species that emit light called labels in ECLIA; co-reactants, which are added reagents that support the luminophore to undergo the excited state; electrodes, which are the place for the ECL reactions to take place; and the format of the immunoassay. This review discusses the behaviour of ECLIA parameters, the required instrumentations, and some important examples of detections based on ECLIA.

Copyrights © 2021






Journal Info

Abbrev

ijc

Publisher

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

Indonesian Journal of Chemistry is an International, peer-reviewed, open access journal that publishes original research articles, review articles, as well as short communication in all areas of chemistry including applied chemistry. The journal is accredited by The Ministry of Research, Technology ...