<![CDATA[Aging is the biggest risk factor for most of the age-related chronic diseases, which carried a heavy health-care costs burden worldwide. These age-related diseases, such as cardiovascular diseases, neurodegenerative diseases, cancers, type2 diabetes and osteoarthritis shared common mechanisms that associate with aging, such as chronic sterile low grade inflammation, cellular senescence, DNA damages and stem cells dysfunctions. In this review, we will first discussed the dietary manipulation, such as caloric restriction as the mean of delaying aging, and we will also review nutraceuticals or natural compounds, and pharmaceutical drugs as the mean for intervention of aging.Proses menua dikaitkan dengan berbagai penyakit kronis terkait-usia. Penyakit-penyakit tersebut, seperti penyakit kardiovaskuler, penyakit neurodegeneratif, kanker, diabetes tipe 2 dan osteoarthritis mempunyai gambaran umum serupa yaitu inflamasi steril kronis kadar rendah, penuaan sel,kerusakan DNA dan disfungsi sel punca. Tinjauan ini berkenaan dengan manipulasi diet berupa restriksi kalori, juga nutraceuticals serta senyawa alami, juga sediaan faramakologis untuk tujuan mengintervensi proses penuaan. ]]>
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