IJCOM
Vol. 1 No. 1 (2021): ijcom

Relationship of Night Shift Work and Breast Cancer

Arnold Fernando (Occupational Medicine Specialist Program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia)
Muhammad Ilyas (Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia)
Indah Suci Widyahening (Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia)



Article Info

Publish Date
09 Jul 2021

Abstract

Background. Breast cancer is the most common cancer among women worldwide. 80% of breast cancer that has been identified in Indonesia has progressed into an advanced stage of malignancy. In 2007, the International Agency for Research on Cancer concluded: shift-work that involves circadian disruption is probably carcinogenic to humans (Group 2A) Aim. This study aims to justify the association between night shift work and breast cancer. Methods. Searching literature for the evidence-based has been conducted with a clinical question through "PICO" method. Then continued with literature searching using the electronic database "PubMed" and "google scholar" search engine. The keyword is "shift work" "night shift" "breast cancer" and combined with MeSH terms and Boolean operation. The inclusion criteria are research on humans, and the exclusion is inaccessible studies, case report studies, and retracted articles. Result. All of the ten prospective studies that have been combined, the weighted average RR was 0.99 (95% CI = 0.95 to 1.03) for any night shift work compared with none. There was no statistically significant heterogeneity across studies (P = .052). ). But if based on a study of more than 20 years, the RR was 1.01 (95% CI = 0.93 to 1.10). And if based on a study of more than 30 years, the combined RR was 1.00 (95% CI = 0.87 to 1.14, P heterogeneity = 0.067. Confidence intervals for the incidence rate ratios on this study are narrow, even for 20 or more years of night shift work (RR = 1.01, 95% CI = 0.93 to 1.10), so these findings exclude a moderate association of breast cancer incidence with long duration night shift work Conclusion. There are insignificant associations between night shift work and breast cancer.

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Journal Info

Abbrev

ijcom

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

IJCOM publishes original research articles, expert opinion, consensus, literature and systematic review as well as commentary focusing on various streams of community health sciences and occupational medicine including health and safety sciences and researches, community and occupational nutrition, ...