Pediatric Sciences Journal
Vol. 1 No. 1 (2020): (Available online 1 June 2020)

The low level of vitamin D3 among Type 1 Diabetes Mellitus (T1DM) children at Saiful Anwar General Hospital, Malang, Indonesia

Harjoedi Adji Tjahjono (Doctoral Program of Medical Science, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia)
Wisnu Barlianto (Pediatrician, Saiful Anwar Hospital, Malang, Indonesia)
Dian Handayani (Pediatrician, Saiful Anwar Hospital, Malang, Indonesia)
Handono Kalim (Associate Professor, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia)



Article Info

Publish Date
02 Feb 2022

Abstract

Background: The Type 1 Diabetes Melitus (T1DM) is a disease which is occurred because of autoimmune destruction in pancreas islet (insulin-producing ß cells). A Failure mechanism of immunoregulator causes inflammatory process in the islets and continue to damage the pancreatic β cell. Vitamin D deficiency may increase the risk of autoimmune diseases including type 1 diabetes mellitus. The aim of this study was to know the level of vitamin D in type 1 diabetes mellitus. Methods: An observational analytic cross-sectional design was conducted among 40 T1DM subjects and 40 healthy controls aged between 10-18-year-old. They were not having local or systemic infection, nor liver and kidney disorders. Vitamin D levels were measured by the ELISA method (ng/ ml). Subjects’ data were collected and processed by 2007 Microsoft Excel software, then analyzed with SPSS version 16.0 for Windows. Results: Most of respondents in T1DM group were female (57.5%) and 15.94±1.00 years old for average age but not statistically significant compared with control group (p>0.05). There was a significant different of the mean level of vitamin D3 in the T1DM group (10.41 + 2,20 ng/ml) compared with control group (18.41 + 1.41 ng/ml) (p<0,05). Conclusion: The level of vitamin D (25 (OH) D3) in the T1 DM group were significantly lower compared to the control group

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Journal Info

Abbrev

pedscij

Publisher

Subject

Health Professions Public Health

Description

Pediatric Sciences Journal (PedSciJ) is published by the Medical Faculty of Brawijaya University, Indonesia, as an Open Access & Peer Reviewed Multidisciplinary Journal. The aims and scope of the Journal include pediatric, neonatal healthcare, and perinatology/ The Journal aims to bridge and ...